Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: H-Phg-OH, 2935-35-5, Name is H-Phg-OH, SMILES is O=C(O)[C@@H](N)C1=CC=CC=C1, belongs to phthalazines compound. In a document, author is Moustafa, Ahmed H., introduce the new discover.
Synthesis, Antiviral, and Antimicrobial Activity of N- and S-Alkylated Phthalazine Derivatives
A series of N-alkylphthalazinone were synthesized by the reaction of phthalazin-1(2H)-one derivatives 1a-c with alkylating agents namely, propargyl, allyl bromide, epichlorohydrin, 1,3-dichloro-2-propanol, 4-bromobutylacetate, and 1-(bromomethoxy) ethyl acetate to give the corresponding N-alkylphthalazinone 2a-c, 3a-c, 5a-c, 6a-c, 7a-c, and 9a-c. Alkylation of phthalazin-1(2H)-thione to give a series from S-alkylphthalazine 12-14 and thioglycosides 15 and 17 was performed. Deprotection of compounds 7a-c, 9a-c, 15, and 17 resulted in the formation of the corresponding products 8a-c, 10a-c, 16, and 18. The structure of newly synthesized compounds was assigned by IR, H-1, C-13 NMR, and elemental analysis. Some of these compounds were screened for antiviral and antimicrobial activity.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 2935-35-5. Recommanded Product: H-Phg-OH.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem