In an article, author is Makarem, S., once mentioned the application of 7507-86-0, Name is 2-Bromo-5-methoxybenzaldehyde, molecular formula is C8H7BrO2, molecular weight is 215.04, MDL number is MFCD00463817, category is phthalazines. Now introduce a scientific discovery about this category, HPLC of Formula: C8H7BrO2.
Electro-Organic Synthesis: An Efficient Method for the Preparation of Nanosized Particles of Phthalazine Derivatives via One-Pot Multicomponent Reactions
Aza heterocyclic compounds are major interest for organic chemists because of their mainly pharmacological activities and clinical applications such as antianxiety, antitumor, anticonvulsant, cardiotonic and vasorelaxant. This contribution describes an electrochemical approach for the preparation of nanosized particles of phthalazine in high yields and very short reaction time. The method is based on the one-pot multicomponent reaction (MCRs) of phthalhydrazide, malononitrile and aldehydes in propanol employing undivided cell in the presence of NaBr as an electrolyte. The product was characterized, after purification, using IR, (HNMR)-H-1, C-13 NMR, MS and SEM. This procedure provides a method by which nanoparticles are synthesized directly from phthalhydrazide, malononitrile and aldehydes insides of a routine protocol for the synthesis of nano particles of organic compounds in which the synthesized organic compound is transformed into nanosized particles using modem high technology, for example ultrahighpressure rapid expansion of supercritical solution, and supercritical antisolvent with enhanced mass transfer. Size reduction is a fundamental unit operation having important applications in pharmacy. It helps to improve solubility and bioavailability, reduce toxicity, enhance release, and provide better formulation opportunities for drugs.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem