Reference of 623-25-6, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 623-25-6, Name is ¦Á,¦Á’-Dichloro-p-xylene, SMILES is ClCC1=CC=C(CCl)C=C1, belongs to phthalazines compound. In a article, author is Dmitrienko, Anton, introduce new discover of the category.
Shedding Light on the Diverse Reactivity of NacNacAl with N-Heterocycles
The aluminum(I) compound NacNacAl (NacNac=[ArNC(Me)CHC(Me)NAr](-), Ar=2,6-iPr(2)C(6)H(3),1) shows diverse and substrate-controlled reactivity in reactions with N-heterocycles. 4-Dimethylaminopyridine (DMAP), a basic substrate in which the 4-position is blocked, induces rearrangement of NacNacAl by shifting a hydrogen atom from the methyl group of the NacNac backbone to the aluminum center. In contrast, C-H activation of the methyl group of 4-picoline takes place to produce a species with a reactive terminal methylene. Reaction of1with 3,5-lutidine results in the first example of an uncatalyzed, room-temperature cleavage of an sp(2)C-H bond (in the 4-position) by an Al(I)species. Another reactivity mode was observed for quinoline, which undergoes 2,2 ‘-coupling. Finally, the reaction of1with phthalazine produces the product of N-N bond cleavage.
Reference of 623-25-6, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 623-25-6 is helpful to your research.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem