4474-86-6, Name is N-Cbz-D-Asparagine, molecular formula is C12H14N2O5, belongs to phthalazines compound, is a common compound. In a patnet, author is Bakherad, Mohammad, once mentioned the new application about 4474-86-6, Safety of N-Cbz-D-Asparagine.
Sonogashira Reaction: Synthesis of Novel Derivatives of 3-Aryl-Substituted 6-Chloroimidazo[2, 1-a]phthalazines Catalyzed by Pd-Cu in Water
The reaction of 1-chloro-4-propargylaminophthalazine with various aryl halides catalyzed by Pd-Cu in the presence of potassium carbonate, as the base, in water leads to the one-pot formation of new derivatives of 3-aryl-substituted-6-chloroimidazo-[2,1-a]phthalazines in moderate-to-good yields. Their structures are confirmed by IR and NMR spectra as well as elemental analyses. All the compounds prepared are screened invitro for their anti-bacterial activities. The preliminary results indicate that some target compounds exhibit promising anti-bacterial potency.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem