Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, 1878-68-8, Name is 4-Bromophenylacetic acid, SMILES is OC(=O)CC1=CC=C(Br)C=C1, belongs to phthalazines compound. In a document, author is Bakherad, Mohammad, introduce the new discover, Computed Properties of C8H7BrO2.
Synthesis of New Derivatives of 1,2,3-Triazole-Linked Phthalazine-1,4-dionein Water: Experimental Aspects and Molecular Docking Calculations
A new series of phthalazine-based 1,2,3-triazole derivatives are synthesized by the reaction of 2-methyl-3-(prop-2-yn-1-yl)-2,3dihydro- phthalazine-1,4-dione or 2,3-bis(prop-2-yn-1-yl)-2,3-dihydrophthalaz- ine-1,4-dione with aromatic azides via coppercatalyzed azide-alkyne cycloaddition reactions in the presence of metformine as a ligand. These reaction procedures have the advantages of high-to-excellent yields, short reaction times, mild experimental conditions, and operational simplicity. All the synthesized compounds are screened in vitro for their antibacterial activities against the three bacterial strains Micrococcus luteus, Pseudomonas aeruginosa, and Bacillus subtilis. Furthermore, the results of anti-bacterial activity of the synthesized compounds was investigated using molecular docking calculations.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1878-68-8 is helpful to your research. Computed Properties of C8H7BrO2.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem