Chemistry, like all the natural sciences, COA of Formula: C7H5BrFNO2, begins with the direct observation of nature¡ª in this case, of matter.502496-34-6, Name is 4-Bromo-2-fluoro-6-nitrotoluene, SMILES is CC1=C([N+]([O-])=O)C=C(Br)C=C1F, belongs to phthalazines compound. In a document, author is Veisi, Hojat, introduce the new discover.
Protic ionic liquid [TMG][Ac] as an efficient, homogeneous and recyclable catalyst for one-pot four-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones and dihydro-1H-pyrano[2,3-c]pyrazol-6-ones
The mildly basic ionic liquid N,N,N,N-tetramethylguanidinium acetate [TMG][Ac] was found to be a very effective basic catalyst for the one-pot, four-component synthesis of 2H-indazolo[2,1-b] phthalazinetriones by condensation of phthalic anhydride, hydrazinium hydroxide, aromatic aldehydes, and dimedone in high yields at 80 degrees C. [TMG][Ac] catalyzed simple and efficient one-pot four-component reaction of Meldrums acid, ethyl acetoacetate, hydrazine hydrate, and aromatic aldehydes to give dihydro-1H-pyrano[2,3-c] pyrazol-6-ones is reported. The ionic liquid could be recycled several times without loss of efficiency with regards to the reaction times and yields.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 502496-34-6. COA of Formula: C7H5BrFNO2.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem