Chemistry, like all the natural sciences, Product Details of 92-92-2, begins with the direct observation of nature¡ª in this case, of matter.92-92-2, Name is [1,1′-Biphenyl]-4-carboxylic acid, SMILES is O=C(C1=CC=C(C2=CC=CC=C2)C=C1)O, belongs to phthalazines compound. In a document, author is Ramezani, Mahin, introduce the new discover.
Synthesis of new (trifluoromethyl)-1H-benzo[e][1,2,4]triazolo[1,2-a] [1,2,4]triazine-1,3(2H)-diones and (trifluoromethyl)benzo[5,6][1,2,4] triazino [1,2-b]phthalazine-8,13-diones
In this paper we investigated reactions of urazole and phthalazine with N-(aryl)-2,2,2-trifluoroacetimidoyl chloride derivatives. Results showed that when imidoyl chloride derivative has a fluorine atom at ortho position (3a-c), in two steps under a S(N)i mechanism and then SNAr reaction mechanism produce ay1-5-(trifluoromethyl)-1H-benzo [el [1,2,4]triazolo[1,2-a] [1,2,4]triazine-1,3(2H)-diones (4a-c) and 6-(trifluoromethyl)benzo[5,6][1,2,4]triazino[1,2-b]phthalazine-8,13-diones (4i,4j) in good to excellent yields. In the other imidoyl derivatives (3d-h and 3i,3j) under these conditions cyclization reaction does not occur and therefore produce 1-aryl-2,2,2-trifluorornethyl)-4-phenyl-1,2,4-triazolidine-3,5-diones (4d-h) and 2-(2,2,2-trifluoro-1-(arylimino)ethyl)-2,3-dihydrophthalazine-1,4-diones(4k,41) (non-cyclic products) in good to excellent yields. (C) 2016 Elsevier B.V. All rights reserved.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 92-92-2. Product Details of 92-92-2.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem