One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 122-99-6, Name is 2-Phenoxyethanol, formurla is C8H10O2. In a document, author is De Abreu, Maxime, introducing its new discovery. Quality Control of 2-Phenoxyethanol.
Phosphoramidates as Transient Precursors of Nitrogen-Centered Radical Under Visible-Light Irradiation: Application to the Synthesis of Phthalazine Derivatives
Phosphoramidates are for the first time presented as efficient N-Centered Radical (NCR) precursors under visible-light irradiation. More precisely among this class of phosphorus-derived compounds, we studied the radical reactivity of phosphonohydrazones, under mild reaction conditions, which allowed the synthesis of a wide and diversified library of the scarcely reported phthalazine scaffold. Mechanistic investigations confirmed the formation of a NCR from these brand-new phosphonohydrazones (derivatived from phosphoramidates), which were further engaged in an intramolecular 6-exo-dig cyclization to provide phthalazines. Compared to other pre-activated moieties, the phosphoramidate group is self-immolative, thus enhancing its attractiveness for the C-N bond formation.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem