Simple exploration of Fmoc-Pra-OH

Synthetic Route of 198561-07-8, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 198561-07-8.

Synthetic Route of 198561-07-8, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 198561-07-8, Name is Fmoc-Pra-OH, SMILES is C#CC[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(O)=O, belongs to phthalazine compound. In a article, author is Elmi-Mehr, Maryam, introduce new discover of the category.

AN EFFICIENT ONE-POT NEAT SYNTHESIS OF PYRAZOLO[1,2-b]PHTHALAZINES USING CELLULOSE SULFURIC ACID AS A BIODEGRADABLE AND RECOVERABLE HETEROGENEOUS CATALYST

An efficient and environmentally friendly procedure for the synthesis of 3-amino-1-aryl-5, 10-dioxo-5,10-dihydro-1H-pyrazolo[1,2-b] phthalazine-2-carbonitriles through the one-pot, three-component reaction of phthalhydrazide, an aromatic aldehyde, and malononitrile in the presence of cellulose sulfuric acid (cellulose-SO3H) is described. The reactions occur under thermal solvent-free conditions and the process is operative with various aromatic aldehydes, giving the corresponding products in high yields. Other beneficial features of this protocol include inexpensive, biodegradable and easily obtained catalyst, avoiding the use of harmful organic solvents, simple work-up, and the recyclability and reusability of the catalyst for up to five consecutive runs.

Synthetic Route of 198561-07-8, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 198561-07-8.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem