Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Raghavendra, G. Jeevan, once mentioned the application of 88-99-3, Name is Pathalic acid, molecular formula is C8H6O4, molecular weight is 166.1308, MDL number is MFCD00002467, category is phthalazine. Now introduce a scientific discovery about this category, Product Details of 88-99-3.
One-Pot Four Component Synthesis of 3-Amino-1-(1H-indol-2-yl)-5,10-dioxo-5,10-dihydro-1H-pyrazolo[1,2-b]phthalazine Derivatives Mediated by [DBUH][OAc]
One-pot, four component, green, and efficient synthesis of 3-amino-1-(5-nitro-1H-indol-2-yl)-5,10-dioxo-5,10-dihydro-1H-pyrazolo[1,2-b]phthalazine derivatives by reaction of phthalic anhydride with hydrazine hydrate, 5-nitro-1H-indole-3-carboxaldehyde-indole-3-carboxaldehydes and malononitrile-ethyl cyanoacetate in the presence of [DBUH][OAc] at 60-65 degrees C is developed. The method is characterized by short reaction time, high yields, and purity of products formed.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem