Application of 622-95-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 622-95-7, Name is 1-(Bromomethyl)-4-chlorobenzene, SMILES is ClC1=CC=C(CBr)C=C1, belongs to phthalazine compound. In a article, author is Zhang Haiming, introduce new discover of the category.
Synthesis and Anticonvulsant Activity Evaluation of Phthalazine and Heterocyclic Derivatives
Four series of derivatives, 6-substituted-1,2,4-triazolo[3,4-a] phthalazine derivatives and 6-substituted tetrazolo[5,1-a] phthalazine derivatives have been synthesized. The structures of compounds are confirmed by H-1 NMR, C-13 NMR, IR and HRMS. The anticonvulsant effects of the compounds are evaluated with maximal electroshock test by intraperitoneally injected in mice. The experimental results show that N-(4-bromophenyl) tetrazolo[5,1-alpha]phthalazin-6-amine (7a) was the most potent compound, with a median effective dose of 5.89 mg circle kg(-1). Its anticonvulsant effect is better than the reference drug, carbamazepine.
Application of 622-95-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 622-95-7 is helpful to your research.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem