Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 5267-64-1, Name is D-Penylalaninol, molecular formula is , belongs to phthalazine compound. In a document, author is Wu, Yan, SDS of cas: 5267-64-1.
Two series of [1,2,4]triazolo[3,4-a]phthalazine and tetrazolo[5,1-a]phthalazine derivatives bearing substituted benzylpiperazine moieties have been synthesized and evaluated for their positive inotropic activity by measuring left atrium stroke volume on isolated rabbit heart preparations. The majority of the derivatives exhibited better in vitro activity than the existing drug, milrinone, and 6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)tetrazolo[5,1-a]phthalazine. 8m in particular was identified as the most potent with an increased stroke volume of 12.02 +/- 0.20% (milrinone: 2.46 +/- 0.07%) at a concentration of 3x105m. The chronotropic effects of the compounds that exhibited good potency were also evaluated.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem