253-52-1, Phthalazine is a phthalazine compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Specific preparation methods are: no special protection, clean air to a single-necked flask were added sequentially magneton, phthalazine(52mg, 0.4mmol), was added sodium iodide (18mg, 30molpercent), 70percent of the mass fraction of the water phase of t-butyl hydroperoxide(152mg, 1.2mmol), then add toluene (728.8mg, 8mmol), toluene as both reactant and as a solvent, the reaction at 150 1Hours TLC showed the starting material is completely consumed phthalazine. Heating was stopped to quench the reaction. Without extraction, direct wetLoading, 200-300 mesh silica gel column chromatography, a mixed solvent of ethyl acetate and petroleum ether (1: 4) rinse. Separated structure of formula IXaFormula compound 84.0mg, 89percent yield;
The synthetic route of 253-52-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Xiangtan University; Yang, Luo; Luo, Wenkun; (17 pag.)CN105503724; (2016); A;,
Phthalazine – Wikipedia
Phthalazine | C8H6N2 – PubChem