Healthcare careers for chemists are once again largely based in laboratories, Product Details of 1821-12-1, although increasingly there is opportunity to work at the point of care, helping with patient investigation. 1821-12-1, Name is 4-Phenylbutanoic acid, SMILES is O=C(O)CCCC1=CC=CC=C1, belongs to phthalazine compound. In a document, author is Lashkari, Mojtaba, introduce the new discover.
A simple synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives via one-pot four-component condensation reaction of phthalimide, hydrazine monohydrate, aromatic aldehyde derivatives and malononitrile in the presence of a catalytic amount of zirconium tetrachloride (ZrCl4) as a mild and efficient Lewis acidic catalyst under thermal and solvent-free conditions with good yields and short reaction times is developed. This present methodology has notable benefits such as high efficiency, inexpensive and non-toxic catalyst, environmentally benign nature, solvent-free conditions and simplicity of operation.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem