The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. In an article, author is Bian, Ming, once mentioned the application of 80382-23-6, Name is Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate, molecular formula is C15H17NaO3, molecular weight is 268.2835, MDL number is MFCD00941425, category is phthalazine. Now introduce a scientific discovery about this category, Product Details of 80382-23-6.
With the aim of finding new anticonvulsant drugs, new 6-substituted-[1,2,4] triazolo[3,4-a] (tetrazolo[5,1-a]) phthalazine derivatives (1-34) have been designed and synthesized. All the compounds were evaluated for their anticonvulsant activities using the maximal electroshock test (MES). Most of the synthesized compounds exhibited potent anticonvulsant activities in the MES. The most promising compound 14 showed significant anticonvulsant activity in MES test with ED50 value of 9.3 mg/kg. It displayed a wide margin of safety with protective index much higher than the standard drug Carbamazepine. And the potency of compound 14 against seizures induced by Pentylenetetrazole, Isoniazid, Thiosemicarbazide and 3-Mercaptopropionic acid in the chemical-induced seizure tests suggested that compound 14 displayed wide spectrum of activity in several models.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 80382-23-6. The above is the message from the blog manager. Recommanded Product: Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem