The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. In an article, author is Chate, Asha V., once mentioned the application of 886-86-2, Name is Ethyl 3-aminobenzoate methanesulfonate, molecular formula is C10H15NO5S, molecular weight is 261.29, MDL number is MFCD00013176, category is phthalazine. Now introduce a scientific discovery about this category, SDS of cas: 886-86-2.
An efficient and green method has been developed for the synthesis of 2H-indazolo[2,1-b]phthalazinetriones derivatives by employing 15 mol% beta-cyclodextrinvia a one-pot multicomponent reaction of aldehyde, dimedone, hydrazine hydrate with succinic anhydrideiphthalic anhydride in water at 80 degrees C for first time. The catalyst could be recovered and reused for four consecutive cycles without appreciable loss in catalytic activity and evaluated for in vitro antimicrobial activity against different Gram-positive and Gram-negative bacterial strains. The outcome of the screening study showed that compound 6d, 6f and 7n exhibited excellent activity against E. coil. Whereas, compound 6f and 6 h exhibited excellent activity against P. aeurginosa, and compound 6c, and 6e displayed again excellent activity against Staphylococcus aureus whereas compound 7o shows excellent activity against S. aureus and B. subtilis when compared with Ampicillin (standard control). The results indicated that maximum compounds are moderately effective against bacterial growth and their effectiveness is highest against standard drugs. (C) 2017 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
Interested yet? Keep reading other articles of 886-86-2, you can contact me at any time and look forward to more communication. Safety of Ethyl 3-aminobenzoate methanesulfonate.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem