Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. Category: phthalazines, 2935-35-5, Name is H-Phg-OH, SMILES is O=C(O)[C@@H](N)C1=CC=CC=C1, in an article , author is Li Jiali, once mentioned of 2935-35-5.
In this paper, a series of 6-substituted-pyrido[3,2-e][1,2,4] triazolo[4,3-a] pyrazine derivatives have been synthesized. Their anticonvulsant activity and neurotoxicity in mice were evaluated by maximal electroshock (MES) and rotarod test, respectively. The structures were confirmed by H-1 NMR, C-13 NMR, MS and HRMS. The experimental results show that 6-phenoxypyrido[3,2-e][1,2,4] triazolo[4,3-a]pyrazine (5g) was safer than the reference drug, carbamazepine, with ED50 value of 93.9 mg.kg(-1) and protective index (PI) value of 24.3, which was a potential anti-epilepsy candidate compound.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 2935-35-5. Formula: https://www.ambeed.com/products/2935-35-5.html.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem