Chemistry involves the study of all things chemical – chemical processes, chemical compositions and chemical manipulation – in order to better understand the way in which materials are structured, how they change and how they react in certain situations. , Related Products of 3648-20-2, 3648-20-2, Name is Diundecyl phthalate, molecular formula is C30H50O4, belongs to phthalazine compound. In a document, author is Sen, Supriti, introduce the new discover.
A systematic study of the reaction of 1,4-dihydrazinophthalazine (DHPH) with 1,3-dicarbonyls [viz., acetylacetone (acac), dibenzoylmethane (bzbz), and 1-benzoylacetone (bzac)] varying the reaction conditions was carried out to obtain the phthalazine derivatives (1-4). One-pot reaction of DHPH with acac led to the formation of two compounds 1 and 2, with various factors such as the presence of the acid or base, amount of the acac, time of reflux, and the temperature. The reaction conditions of DHPH with bzbz or bzac are sort of different to isolate the products 3 and 4, respectively. The derivatives (1-4) have been characterized by elemental analyses, H-1 NMR, and electrospray ionization-mass spectrometry (ESIMS) and the cytotoxic activity of the compounds 1-4 was evaluated on HeLa cell line. [Supplementary materials are available for this article. Go to the publisher’s online edition of Synthetic Communications (R) for the following free supplemental resource(s): Full experimental and spectral details.]
Related Products of 3648-20-2, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 3648-20-2.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem