Name: 2-Benzamidoacetic acid, Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. 495-69-2, Name is 2-Benzamidoacetic acid, SMILES is O=C(O)CNC(C1=CC=CC=C1)=O, belongs to phthalazine compound. In a article, author is Dam, Binoyargha, introduce new discover of the category.
Nano-organocatalyzed one-pot four-component reactions for the synthesis of phthalazine-trione/dione derivatives have been devised for the first time from easily accessible starting materials under solvent-free conditions. This methodology showed very good substrate scope and high degree of tolerance for a variety of aldehydes (including aliphatic and heteroaromatic aldehydes) and active methylene compounds. Moreover, the catalyst can be easily separated from the reaction mixture because of its highly paramagnetic nature, by using an external magnet, and can be reused in five more consecutive runs without much decrease in catalytic activities. Other significant advantages of this method are shorter reaction time, good yield, simple work-up procedure, easy catalyst handling etc.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem