The prevalence of solvent effects in heterogeneous catalysis in condensed media has motivated developing quantitative kinetic, and theoretical assessments of solvent structures and their interactions with reaction intermediates and transition states. 886-86-2, Name is Ethyl 3-aminobenzoate methanesulfonate, molecular formula is C10H15NO5S, belongs to phthalazine compound. In a document, author is Wang, Haitao, introduce the new discover, Product Details of 886-86-2.
Novel amino-acid-derived phthalazine reagents have been designed and synthesized for the enantioselective fluorocyclizations of prochiral indoles. The scope of reaction is evidenced by 28 examples of fluorinated furoindole and pyrroloindole heterocycles bearing various functionalities with up to 99% ee. The resulting enantioenriched fluorinated products are found to be potent AChE inhibitors. Advantages of the current new chiral reagents include ease in the synthesis of analogues and readily tunable steric/electronic demands.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem