Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. Recommanded Product: 4,4′-Methylenebis(2-methylaniline), 838-88-0, Name is 4,4′-Methylenebis(2-methylaniline), SMILES is NC1=CC=C(CC2=CC=C(C(C)=C2)N)C=C1C, in an article , author is Abouzid, Khaled A. M., once mentioned of 838-88-0.
A series of new phthalazine derivatives 3a-i and 4a-c were synthesized via the reaction of 1-chlorophthalazine derivative 2 with either N-substituted-piperazines, primary or their secondary amines. The structure of the synthesized, new compounds were characterized by spectral data. The anti-proliferative activity on human breast cancer cell line MCF-7 of the synthesized compounds was determined. The results showed that six of the test compounds (3a, 3g, 3i, and 4a-c) displayed potent cytotoxic activity ranging from 1.4 to 2.3 mu mol.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem