Recently I am researching about 3CL PROTEASE INHIBITORS; BIOLOGICAL EVALUATION; TANDEM REACTION; SELECTIVE INHIBITORS; DESIGN; DERIVATIVES; POTENT; ARYL; OXAZOLES; KETONES, Saw an article supported by the Natural Science Foundation of Jiangsu ProvinceNatural Science Foundation of Jiangsu Province [BK20171184]; Jiangsu Planned Projects for Postdoctoral Research Funds [1701132C]; Technology Plan Projects of Xuzhou [KC17091]; Postgraduate Research & Practice Innovation Program of Jiangsu Province [KYCX18-2203]. Category: phthalazines. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Huang, TH; Wu, X; Yu, YB; An, L; Yin, XX. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid
A convenient and efficient strategy for the synthesis of 2-acyl benzothiazoles/thiazoles has been developed. The treatment of benzothiazole/thiazole with allylic Grignard reagents readily generates the corresponding 2-Grignard reagents, which is followed by a reaction with N,N’-carbonyldiimidazole activated carboxylic acids to afford various 2-acyl benzothiazoles/thiazoles products. The synthetic method is applicable to a wide array of carboxylic acids and allows easy access to 2-acyl benzothiazoles/thiazoles with considerable yields under mild reaction conditions. (C) 2019 Elsevier Ltd. All rights reserved.
Category: phthalazines. About 4-Nitrobenzoic acid, If you have any questions, you can contact Huang, TH; Wu, X; Yu, YB; An, L; Yin, XX or concate me.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem