Recommanded Product: 4-Nitrobenzoic acid. I found the field of Chemistry very interesting. Saw the article POCl3 promoted metal-free synthesis of tertiary amides by coupling of carboxylic acids and N,N-disubstituted formamides published in 2019, Reprint Addresses Xiao, JH (corresponding author), State Key Lab NBC Protect Civilian, Beijing, Peoples R China.. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid.
Herein we report a robust and synthetically useful catalyst-free amination methodology by the coupling of carboxylic acids and N-substituted formamides using POCl3 as a promoter. Versatile amides with a wide array of substituent groups were prepared within only 1 h in good to excellent yields. And even multi-substituted aromatic carboxylic acids could give the desired products with satisfactory results.
Recommanded Product: 4-Nitrobenzoic acid. Bye, fridends, I hope you can learn more about C7H5NO4, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem