Recently I am researching about TRANSFORMATION; ASSIGNMENT, Saw an article supported by the JSPS KAKENHIMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) [JP15H05904]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Tanabe, S; Kobayashi, Y. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid. HPLC of Formula: C7H5NO4
(18R)-and (18S)-stereoisomers of resolvin E3 (RvE3), potent anti-inflammatory mediators, were synthesized stereo-and enantioselectively through the Wittig reaction of the carbonate of 6R,7R- and 6R,7S-dihydroxynona-2E, 4E-dienal, a C12-C20 part, with the phosphonium salt corresponding to the C1-C11 part. The stereoisomeric carbonate was prepared by the Swern oxidation of 3-(AcO)-6R, 7R-or 3-(AcO)6R, 7S-(dihydroxy-carbonate)-4-nonen-1-ol followed by the spontaneous elimination of the AcO group in one pot. The (6R, 7R)-(dihydroxy-carbonate)-alcohol for (18R)-RvE3 was, in turn, provided by stereoselective epoxidation of 9-(TBS-oxy) nona-4Z, 6E-dien-3R-ol with m-CPBA and the subsequent Pd-catalyzed addition of AcOH to the resulting syn vinyl epoxy alcohol followed by carbonate formation of the vic-syn-diol and TBS desilylation. The Mitsunobu inversion of the syn vinyl epoxy alcohol gave the anti isomer, which was converted to 3-(AcO)-6R, 7S-(dihydroxy-carbonate)-4-nonen-1-ol, the intermediate to (18S)-RvE3, by the same set of reactions.
HPLC of Formula: C7H5NO4. Bye, fridends, I hope you can learn more about C7H5NO4, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem