I found the field of Chemistry very interesting. Saw the article Isothiourea-Catalysed Regioselective Acylative Kinetic Resolution of Axially Chiral Biaryl Diols published in 2019.0. COA of Formula: C7H5NO4, Reprint Addresses Smith, AD (corresponding author), Univ St Andrews, Sch Chem, EaStCHEM, St Andrews KY16 9ST, Fife, Scotland.. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid
An operationally simple isothiourea-catalysed acylative kinetic resolution of unprotected 1,1 ‘-biaryl-2,2 ‘-diol derivatives has been developed to allow access to axially chiral compounds in highly enantioenriched form (s values up to 190). Investigation of the reaction scope and limitations provided three key observations: i) the diol motif of the substrate was essential for good conversion and high s values; ii) the use of an alpha,alpha-disubstituted mixed anhydride (2,2-diphenylacetic pivalic anhydride) was critical to minimize diacylation and give high selectivity; iii) the presence of substituents in the 3,3 ‘-positions of the diol hindered effective acylation. This final observation was exploited for the highly regioselective acylative kinetic resolution of unsymmetrical biaryl diol substrates bearing a single 3-substituent. Based on the key observations identified, acylation transition state models have been proposed to explain the atropselectivity of this kinetic resolution.
COA of Formula: C7H5NO4. Welcome to talk about 62-23-7, If you have any questions, you can contact Qu, S; Greenhalgh, MD; Smith, AD or send Email.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem