An article Tris(o-phenylenedioxy)cyclotriphosphazene as a Promoter for the Formation of Amide Bonds Between Aromatic Acids and Amines WOS:000579422600012 published article about CARBOXYLIC-ACIDS; PHOSPHONITRILIC COMPOUNDS; DEHYDRATIVE CONDENSATION; DIRECT AMIDATION; LEWIS-ACIDS; HYDROLYSIS; ACTIVATION; CATALYST; DICYCLOHEXYLCARBODIIMIDE; FORMYLATION in [Movahed, Farzaneh Soleymani; Bagal, Dattatraya B.; Saito, Susumu] Nagoya Univ, Grad Sch Sci, Chikusa Ku, Nagoya, Aichi 4648602, Japan; [Sawant, Dinesh N.; Saito, Susumu] Nagoya Univ, Res Ctr Mat Sci, Chikusa Ku, Nagoya, Aichi 4648602, Japan in 2020.0, Cited 72.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. Application In Synthesis of 4-Nitrobenzoic acid
The atom-efficient formation of amide bonds has emerged as a top-priority research field in organic synthesis, as amide bonds constitute the backbones of proteins and represent an important structural motif in drug molecules. Currently, the increasing demand for novel discoveries in this field has focused substantial attention on this challenging subject. Herein, the degradable 1,3,5-triazo-2,4,6-triphosphorine (TAP) motif is presented as a new condensation system for the dehydrative formation of amide bonds between diverse combinations of aromatic carboxylic acids and amines. The underlying reaction mechanism was investigated, and potential catalyst intermediates were characterized using(31)P NMR spectroscopy and ESI mass spectrometry.
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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem