Novel rearrangement of a diaziridine was written by Heine, Harold W.;Lehman, Laura S.;Glaze, Alan P.;Douglas, Alan W.. And the article was included in Journal of Organic Chemistry in 1980.Quality Control of 2-Methyl-2,3-dihydrophthalazine-1,4-dione This article mentions the following:
Diaziridine I isomerizes in refluxing toluene or in Me2SO solutions containing KOCMe3 into the phthalazinone II. The structure of II was characterized by 13C and 1H NMR and by alk. hydrolysis and N-methylation. In the experiment, the researchers used many compounds, for example, 2-Methyl-2,3-dihydrophthalazine-1,4-dione (cas: 18393-54-9Quality Control of 2-Methyl-2,3-dihydrophthalazine-1,4-dione).
2-Methyl-2,3-dihydrophthalazine-1,4-dione (cas: 18393-54-9) belongs to phthalazine derivatives. Like many other isomeric benzodiazines, phthalazine derivatives reveal numerous pharmacological and biological activities such as anticonvulsant, antitumor, antiproliferative, antiepileptic, anti-inflammatory, and vasorelaxant. As with cinnolines, phthalazines were also prepared most frequently through condensations of hydrazine derivatives and carbonyl-containing compounds.Quality Control of 2-Methyl-2,3-dihydrophthalazine-1,4-dione
Referemce:
Phthalazine – Wikipedia,
Phthalazine | C8H6N2 – PubChem