With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.89898-86-2,5-Nitrophthalazine,as a common compound, the synthetic route is as follows.
(C) Phthalazine-5,8-dione precursors (Y1 and Y4=C, Y2 and Y3=N) used in the process of the present invention were prepared according to the following reaction scheme 4. The detailed procedure is described in (i) J. Med. Chem., 48, 744-752, and (ii) Bioorganic and Medical Chemistry Letters, 27, 2577-2580.
The synthetic route of 89898-86-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Gerogetown University; Brown, Milton L.; Paige, Mikell; Torestsky, Jeffrey A.; Uren, Aykut; Kosturko, George; Bulut, Gullay; (58 pag.)US9522908; (2016); B2;,
Phthalazine – Wikipedia
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