253-52-1, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 253-52-1, Name is Phthalazine,introducing its new discovery.
2,3-Dihydrofurans as Potential Cytotoxic and Antibacterial Agents: Tandem Knoevenagel?Michael Cyclization for the Synthesis of 2,3-Dihydrofurans by Using alpha-Tosyloxy Ketone Precursors
Novel 2,3-dihydrofuran derivatives were synthesized through a tandem Knoevenagel?Michael cyclization in good yield by reacting alpha-tosyloxy ketone, 5,5-dimethyl-1,3-cyclohexanedione, and various aldehydes in the presence of phthalazine in acetonitrile. These compounds were subjected to in vitro antibacterial screening against eight micro-organisms by using diffusion method and also in vitro cytotoxicity screening against four human cancerous cell lines by applying MTT assay. Some of the compounds showed impressive activities.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 253-52-1, and how the biochemistry of the body works.253-52-1
Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N223 – PubChem