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Chemistry, like all the natural sciences, Product Details of 23981-47-7, begins with the direct observation of nature— in this case, of matter.23981-47-7, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, SMILES is O=C(O)CC1=CC=C2C=C(OC)C=CC2=C1, belongs to phthalazine compound. In a document, author is Mohammad, Faruq, introduce the new discover.

In this, we performed a four component domino reaction of phthaloyl dichloride, hydrazine hydrate, indole-3-carboxaldehydes and malononitrile/ethyl cyanoacetate to form 1-(1H-indol-2-yl)-1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives by in situ generation of HCl as catalyst in refluxing ethanol for 1 h in good yields. This four component domino reaction transformation presumably proceeds via addition/dehydrohalogenation/condensation/cyclization of reactions. The material was thoroughly characterized at various stages of its formation by means of FTIR, NMR spectroscopic and Mass spectrometric analysis and is confirmed to be the derivative of 1-(1H-indo1-2-yl)-1H-pyrazolo [1,2-b]phthalazine-5,10-dione.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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Reference of 23981-47-7, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 23981-47-7 is helpful to your research.

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An efficient one-pot synthesis of 1 H-indazolo[1,2-b]phthalazine-trione and spiro-triazolo[1,2-a]indazole-tetraone derivatives via three-component condensation reaction of phthalhydrazide or 4-phenylurazole, aldehydes or isatins and dimedone in the presence of a catalytic amount of silica-supported tungstic acid (STA), as a heterogeneous solid acid catalyst under solvent-free conditions is presented. This ecofriendly protocol offers several advantages such as a cost-effective procedure with excellent yields, short reaction time, simple workup, recovery and reusability of catalyst with broad scope of usable substrates. This has made the protocol sustainable and economic.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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In an article, author is Mohamadpour, Farzaneh, once mentioned the application of 23981-47-7, HPLC of Formula: https://www.ambeed.com/products/23981-47-7.html, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, molecular formula is C13H12O3, molecular weight is 216.2326, MDL number is MFCD00033105, category is phthalazine. Now introduce a scientific discovery about this category.

Catalyst-free three-component tandem approach can synthesize spimacenaphthylenes and 1H-pyrazolo [1,2-b] phthalazine-5,10-diones by Knoevenagel-Michael cyclocondensation via visible light irradiation in aqueous ethyl lactate at room temperature. The significant advantages of the present protocol include energy-effectiveness, catalyst-free, excellent yields, operational simplicity, high atom-economy, commercially accessible, inexpensive preliminary substances, so it meets some features of sustainablility and green chemistry.

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Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 23981-47-7, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, molecular formula is C13H12O3. In an article, author is Lamera, Esma,once mentioned of 23981-47-7, Formula: https://www.ambeed.com/products/23981-47-7.html.

A new, convenient, and efficient method for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones is developed starting from phthalhydrazide, aromatic aldehydes, and malononitrile using 4-N, N-dimethylaminopyridin as catalyst. This modified route provides much higher yields and a simple work-up procedure of products. Also this methodology is of interest due to the use of ethanol as a solvent without use of any toxic metals as catalyst, thus minimizing the cost, the operational hazards, and environmental pollution.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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23981-47-7, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, molecular formula is C13H12O3, belongs to phthalazine compound, is a common compound. In a patnet, author is Reddy, Mudumala Veeranarayana, once mentioned the new application about 23981-47-7, Computed Properties of https://www.ambeed.com/products/23981-47-7.html.

A simple, efficient, and green practical approach to 1H-pyrazolo[1,2-b]phthalazine-5,10-diones from phthalhydrazide, aldehydes, and malononitrile/ethyl cyanoacetate has been developed that uses inexpensive and readily available InCl3 as a catalyst in solvent-free one-pot three-component cyclo condensation reaction. This method should provide high yields, shorter reaction time, easy work-up, purification of products by nonchromatographic method, and cleaner reaction. It is a new strategy for N-fused heterocycles synthesis, which haswider application in organic and medicinal chemistry. (c) 2013 Elsevier Ltd. All rights reserved.

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Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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Synthetic Route of 23981-47-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 23981-47-7 is helpful to your research.

Synthetic Route of 23981-47-7, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 23981-47-7, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, SMILES is O=C(O)CC1=CC=C2C=C(OC)C=CC2=C1, belongs to phthalazine compound. In a article, author is VirupakshiPrabhakar, introduce new discover of the category.

The article is aimed to synthesize, characterize and screening the biological activity of novel a series of 6-(Thiophen-3-Yl)-3-Para-Substituted-[1,2,4] Triazolo[3,4-a] Phthalazine Derivatives (8 a-j) with good yields. The newly synthesized compounds were characterized by IR, H-1-NMR, C-13 NMR and Mass spectral data. The anti-microbial activity of the novel compounds were screened by disc diffusion method. Compounds 8h, 8g, and 8f demonstrated good antimicrobial activity against all the tested microbial strains. FusedPhialazine 1, 2,4 Triazole linked thiophene with 2,5 di fluoro nucleus has shown good antibacterial and antifungal activities.

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Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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23981-47-7, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, molecular formula is C13H12O3, Recommanded Product: 2-(6-Methoxynaphthalen-2-yl)acetic acid, belongs to phthalazine compound, is a common compound. In a patnet, author is Sherif, Yousery E., once mentioned the new application about 23981-47-7.

1,4-Dioxo-3, 4, 4e, 5, 10, 10a-hexahydro-1H-5,10-benzenobenzo [g] phthalazin-2-yl-thioamide [6a]; 1,4-dioxo-3, 4, 4e, 5, 10, 10a-hexahydro-1H-5, 10-benzenobenzo [g] phthalazin-2-yl-N-pyridylthioamide [6b] and 1,4-dioxo-3, 4, 4e, 5, 10, 10a-hexahydro-1H-5, 10-benzenobenzo[g]phthalazin-2-yl-N-ethylthioamide [6c] and their [Cu(6a-H)(OAc)], [Zn(6a-H)(OAc)], [Cu(6b-H)(H2O)(2)(OAc)]center dot 3H(2)O and [Zn(6b-H)(OAc)], [Cu-2(6c-H)](OAc)(3)]center dot 2H(2)O and [Zn(6c-H)(OAc)] complexes have been synthesized via a reaction between phthalazinedione 6a-c derivatives and the acetate salt of Cu(II) or Zn(II). These compounds were characterized by elemental analysis, spectra (UV-Vis, IR, H-1 NMR, C-13 NMR, ESR), conductance, thermal analysis and magnetic moments.

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Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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Related Products of 23981-47-7, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 23981-47-7 is helpful to your research.

Related Products of 23981-47-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 23981-47-7, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, SMILES is O=C(O)CC1=CC=C2C=C(OC)C=CC2=C1, belongs to phthalazine compound. In a article, author is Rostami, Amin, introduce new discover of the category.

N-Propylsulfamic acid supported onto magnetic Fe3O4 nanoparticles (MNPs-PSA) was used as an efficient and magnetically recoverable catalyst for synthesis of 2H-Indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives from the three-component, one-pot condensation reaction of phthalhydrazide, aromatic aldehydes and cyclic 1,3-diones, in good to excellent yields at 100 degrees C under solvent-free conditions. The catalyst was easily separated with the assistance of an external magnetic field from the reaction mixture and reused for several consecutive runs without significant loss of its catalytic efficiency. In order to compare, the synthesis of 2H-Indazolo [2,1-b]phthalazine-1,6,11(13H)-trione derivatives in the presence of catalytic amount of sulfamic acid (SA) under same reaction condition was also reported.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Abdesheikhi, Mitra, once mentioned the application of 23981-47-7, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, molecular formula is C13H12O3, molecular weight is 216.2326, MDL number is MFCD00033105, category is phthalazine. Now introduce a scientific discovery about this category, Name: 2-(6-Methoxynaphthalen-2-yl)acetic acid.

The one-pot, four-component reaction of phthalic anhydride, hydrazine hydrate, aromatic aldehydes and malononitrile afford 3-amino-1aryl-5,10-dioxo-1H-pyrazolo[1,2-b]phthalazine-2-carbonitrile derivatives in the presence of potassium carbonate in ethanol under reflux conditions. These conditions offer simplified operation, easy purification, excellent yields and environmentally benign reaction conditions. Also, this method avoids the use of expensive catalysts, toxic solvents and chromatographic separation.

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Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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Related Products of 23981-47-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 23981-47-7, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, SMILES is O=C(O)CC1=CC=C2C=C(OC)C=CC2=C1, belongs to phthalazine compound. In a article, author is Nikoorazm, Mohsen, introduce new discover of the category.

Synthesis and characterization of Ni(II)-Vanillin-Schiff base-MCM-41 composite as an efficient and reusable nanocatalyst for multicomponent reactions

An efficient heterogeneous catalyst (Ni(II)-Vanillin-Schiff base-MCM-41) has been synthesized by immobilization of nickel(II)-vanillin complex on MCM-41 nanostructure and characterized by XRD, TGA, BET, EDS, SEM, ICP-OES, TEM and FT-IR spectroscopy. The catalytic activity and stability of the prepared compound has been studied in some multicomponent reactions with polyhydroquinoline, 1H-indazolo [1,2-b] phthalazine-trione and 2,3-dihydroquinazolin-4(1H)-one derivatives under mild condition reactions. All the reactions were carried out in the presence of water as the solvent and under solvent-free conditions. The simple work up, mild conditions, excellent yield, inexpensive and non-toxic catalyst; makes this protocol both attractive and economically viable. More importantly, this catalyst can be reused several times without any significant loss of its catalytic activity.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem