Category: 3648-20-2

Reference of 3648-20-2, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 3648-20-2, Name is Diundecyl phthalate, SMILES is O=C(OCCCCCCCCCCC)C1=CC=CC=C1C(OCCCCCCCCCCC)=O, belongs to phthalazines compound. In a article, author is Patil, Audumbar, introduce new discover of the category.

Deep eutectic solvent an efficient reaction medium for the synthesis of chromeno pyrazolo and indazolo phthalazine derivatives

The volatile, harmful and hazardous solvents have impact on human health, all organisms and environment. To reduce the use of hazardous volatile solvents, there is need to develop the alternative green reaction medium for organic transformations and is the main goal of green chemistry. The green solvent should be nonvolatile, nontoxic, biodegradable and biorenewable. Considering these parameters, herein, we have reported an efficient and environmentally benign green synthesis of chromeno pyrazolo and indazolo phthalazine derivatives in deep eutectic solvent. The present protocol contains excellent yield of the product, short reaction time, operation simplicity, reusability of solvent and no need of further purification.

Reference of 3648-20-2, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 3648-20-2 is helpful to your research.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry is an experimental science, Formula: C30H50O4, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 3648-20-2, Name is Diundecyl phthalate, molecular formula is C30H50O4, belongs to phthalazines compound. In a document, author is Roy, Harendra Nath.

Efficient and convenient synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives mediated by L-proline

An efficient, four-component, one-pot condensation reaction of phthalimide or phthalic anhydride, aromatic aldehydes, and ethyl cyanoacetate for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives mediated by L-proline in excellent yields is reported. [GRAPHICS] .

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 3648-20-2, in my other articles. Formula: C30H50O4.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Electric Literature of 3648-20-2, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 3648-20-2, Name is Diundecyl phthalate, SMILES is O=C(OCCCCCCCCCCC)C1=CC=CC=C1C(OCCCCCCCCCCC)=O, belongs to phthalazines compound. In a article, author is Boraei, Ahmed T. A., introduce new discover of the category.

Design and synthesis of new phthalazine-based derivatives as potential EGFR inhibitors for the treatment of hepatocellular carcinoma

Searching for new leads in the battle of cancer will never ends, we herein disclose the design and synthesis of new phthalazine derivatives and their in vitro and in vivo testing for their antiproliferative activity. Phthalazine was selected as a privilege moiety that is incorporated in a big number of anticancer drugs in clinical use or that are still under clinical or preclinical studies. We utilized the drug extension strategy to tailor the designed compounds to fit the EGFR hydrophobic sub pocket and cleft region. The designed phthalazine derivatives was synthesized by linking phthalazine moiety with 1,3,4-oxadiazole-thione and 1,2,4-triazole-thione. Alkylation and glycosylation of the new heterocyclic systems were successfully performed to be used in the drug extension. Coupling of some phthalazine derivatives with different amino acids was also performed to improve the drug selectivity. The synthesized compounds were tested for their antiproliferative activity against cancer cells both in vivo and in vitro. The in vitro activity against hepatocellular carcinoma (HepG2 cell line) ranged from 5.7 mu g/mL to 43.4 mu g/mL. Compounds 31a and 16 were the most active with an IC(50)5.7 mu g/mL and 7.09 mu g/mL, respectively compared to the standard compound doxorubicin (4.0 mu g/mL). In vivo, compounds 10 and 16 showed IC50 values 7.25 mu g/mL and 7.5 mu g/mL, respectively compared to the standard compound cisplatin (IC50, 9.0 mu g/mL). In silico, testing of the phthalazine derivatives showed that they are good inhibitors for EGFR. The docking studies substantiated compounds 4, 10, 16 and 31a as new lead compounds and identified Arg841 as a key residue in the cleft region for binding stronger inhibitors.

Electric Literature of 3648-20-2, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 3648-20-2.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Category: phthalazines, 3648-20-2, Name is Diundecyl phthalate, molecular formula is C30H50O4, belongs to phthalazines compound. In a document, author is Dong, Yong Ping, introduce the new discover.

Enhancing and inhibiting effects of benzenediols on chemiluminescence of a novel cyclometallated iridium(III) complex

A novel chemiluminescence (CL) system, including the cyclometallated iridium(III) complex {tris[1-(2,6-dimethylphenoxy)-4-(4-chlorophenyl)phthalazine]iridium}, potassium permanganate and oxalic acid, is proposed for the determination of benzenediols. This method is based on the fact that hydroquinone and catechol exhibited an inhibiting effect, while resorcinol exhibited an enhancing effect on CL intensity. The optimum conditions for CL emission were investigated. Under optimal conditions, the detection limits of hydroquinone, catechol and resorcinol were 6.4?x?10-8, 2.7?x?10-9 and 8.1?x?10-7?mol/L, respectively. The method has been successfully applied to the determination of benzenediols in different types of water sample. The luminophors of the CL systems were all identified as the metalligand charge-transfer (MLCT) excited state of the iridium complex. Copyright (c) 2011 John Wiley & Sons, Ltd.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 3648-20-2. Category: phthalazines.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 3648-20-2, Name is Diundecyl phthalate, molecular formula is , belongs to phthalazines compound. In a document, author is Ye, Shang-hui, SDS of cas: 3648-20-2.

Solution processed single-emissive-layer white organic light-emitting diodes based on fluorene host: Balanced consideration for color quality and electroluminescent efficiency

Cost-effective fabrication of white organic light-emitting diodes (WOLED) is meaningful toward commercial application of environment-friendly solid-state lighting sources. Electroluminescent efficiency and color quality are two opposite performance characteristics facing solution processed WOLEDs requiring balanced consideration. Herein, a recently synthesized molecule of 4,4′-(9,9′-(1,3-phenylene) bis(9H-fluorene-9,9-diyl)) bis(N,N-diphenylaniline) (DTPAFB) is introduced as a host material for solution processed all-phosphor WOLEDs, embracing four well-known molecules which are blue iridium (III) bis(2-(4,6-difluorophenyl) pyridinato-N,C-2)(picolinate) (FIrpic), green iridium (III) bis[2-(2-pyridinyl-N) phenyl-C](2,4-pentanedionato-O-2,O-4)[Ir(ppy)(2)(acac)], and orange iridium (III) bis(2-phenyl-benzothiazole-C-2, N)(acetylacetonate) [Ir(bt)(2)(acac)] plus a home-made red phosphor of iridium (III) tris(1-(2,6dimethylphenoxy)-4-(4-chlorophenyl) phthalazine) [Ir(MPCPPZ)(3)]. Illumination quality white light with high brightness, high efficiency, suitable correlated color temperature (CCT), high color-rendering index (CRI), and stable electroluminescent (EL) emission is obtained. A stable white emission with a CRI over 70, Commission Internationale de L’Eclairage (CIE) of (0.37, 0.42), and high EL efficiency of 19.6 lm W-1 at high luminance of 2000 cd m(-2) for blue/orange complementary color WOLEDs is demonstrated. The optimized red/green/blue three primary color WOLEDs show improved CRI up to 81, moderate high efficiency of 25.8 cd A(-1), 14.4 lm W-1, and EQE of 13.9%. Furthermore, the red/green/blue/orange four primary color WOLEDs show the optional balance between color quality and EL efficiency with high CRI of around 81-83 and medium CCT of 3755-3929 K which is warm and soft to human eyes. At an illumination relevant luminance of 1000 cd m(-2), the total power efficiency reaches 33.6 lmW(-1), and still remains 30.2 lm W-1 at 3000 cd m(-2), approaching the efficiency of state-of-the-art fluorescent-tube (40 – 70 lm W-1), potentially suitable as an environment-friendly solid-state lighting source. This work indicates that developing high performance host materials and highly efficient phosphors and carefully combining them with common phosphors is an effective way toward high performance WOLEDs. (C) 2016 Elsevier B.V. All rights reserved.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 3648-20-2, in my other articles. SDS of cas: 3648-20-2.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem