Category: 402-50-6

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 402-50-6, Name is 1-(Trifluoromethyl)-4-vinylbenzene, molecular formula is C9H7F3. In an article, author is Khidre, Rizk E.,once mentioned of 402-50-6, COA of Formula: https://www.ambeed.com/products/402-50-6.html.

Synthesis and Antimicrobial Activity of Novel Heterocycles Utilizing 3-(1,4-Dioxo-3,4-dihydrophthalazin-2(1H)-yl)-3-oxopropanenitrile as Precursors

The reaction of 3-(1,4-dioxo-3,4-dihydrophthalazin-2(1H)-yl)-3-oxopropanenitrile 1 and salicyladehyde furnished coumarin derivatives 4 and 5. Coupling reaction of 1 with aryl diazonium chlorides and benzene-1,4-bis (diazonium) chloride gave the corresponding hydrazones 6a,b and bishydrazone 9, respectively. Hydrazones 6 underwent intramolecular cyclization upon treating with hydrazine hydrate to give 3-aminopyrazoles 7. Pyranyl phthalazine 13 was prepared from the reaction of 1 with ethyl 2-cyano-3-ethoxyacrylate 10. Enaminonitrile 14 was reacted with hydrazine hydrate/phenylhydrazine and hydroxylamine to afford the corresponding pyrazoles 16 and oxime 17. The antimicrobial evaluation revealed pyrazole derivatives 7a,b and 16a,b displayed a broad spectrum activity against most strains. 3-Aminopyrazole derivative 7b showed potent antibacterial activity against all tested microorganisms.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 402-50-6 is helpful to your research. Safety of 1-(Trifluoromethyl)-4-vinylbenzene.

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 402-50-6, Name is 1-(Trifluoromethyl)-4-vinylbenzene, SMILES is FC(F)(F)C1=CC=C(C=C)C=C1, belongs to phthalazine compound. In a document, author is Farahmand, Shohreh, introduce the new discover, Safety of 1-(Trifluoromethyl)-4-vinylbenzene.

Pentaerythritol as efficient H-bonding organocatalyst for synthesis of indazolo[2,1-b]phthalazine-trione derivatives

Pentaerythritol was applied as an effective, biodegradable, nontoxic, mild, and commercially available H-bonding organocatalyst for synthesis of indazolo[2,1-b]phthalazine-trione derivatives via one-pot three-component condensation of aromatic aldehydes, phthalhydrazide, and dimedone under thermal solvent-free conditions in high to excellent yield.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 402-50-6 is helpful to your research. Safety of 1-(Trifluoromethyl)-4-vinylbenzene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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Application of 402-50-6, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 402-50-6.

Application of 402-50-6, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 402-50-6, Name is 1-(Trifluoromethyl)-4-vinylbenzene, SMILES is FC(F)(F)C1=CC=C(C=C)C=C1, belongs to phthalazine compound. In a article, author is Gol’dberg, A. E., introduce new discover of the category.

Crystal structure of a trinuclear complex of zinc(II) with 2,6-Di-tert-butyl-p-quinone 1′-phthalazinylhydrazone

2,6-Di-tert-butyl-p-quinone 1′-phthalazynylhydrazone (HL) is synthesized; the total energies and geometry of the possible hydrazone tautomeric forms are calculated by quantum chemical methods. The hydrazone phthalazone tautomer is shown to be the most stable, which is well consistent with the H-1 NMR spectroscopic data for hydrazone. An X-ray crystallographic analysis is performed of the hydrazone-based Zn(II) trinuclear complex, in which zinc atoms are linked by the diazine bridge of the phthalazine cycle and two pivalate bridges. The geometric properties of the monodeprotonated hydrazone residue in the complex are similar to the calculated data for the phthalazone hydrazone tautomeric form.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Now Is The Time For You To Know The Truth About 402-50-6

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 402-50-6. Formula: C9H7F3.

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Formula: C9H7F3, 402-50-6, Name is 1-(Trifluoromethyl)-4-vinylbenzene, molecular formula is C9H7F3, belongs to phthalazine compound. In a document, author is Sanchez-Moreno, Manuel, introduce the new discover.

Phthalazine Derivatives Containing Imidazole Rings Behave as Fe-SOD Inhibitors and Show Remarkable Anti-T. cruzi Activity in Immunodeficient-Mouse Mode of Infection

A series of new phthalazine derivatives 1-4 containing imidazole rings were prepared. The monoalkylamino substituted. derivatives 2 and 4 were more active in vitro against T. cruzi and less toxic against Vero cells than both their disubstituted analogues and the reference drug benznidazole. Compounds 2 and 4 highly inhibited the antioxidant parasite enzyme Fe-SOD, and molecular modeling suggested that they interact with the H-bonding system of the iron atom moiety. In vivo tests on the acute phase of Chagas disease gave parasitemia inhibition values twice those of benznidazole, and a remarkable decrease in the reactivation of parasitemia was found in the chronic phase for immunodeficient mice. Glucose metabolism studies showed that compounds 1-4 did not affect the succinate pathway but originated important changes in the excretion of pyruvate metabolites. The morphological alterations found in epimastigotes treated with 1-4 confirmed extensive cytoplasm damage and a high mortality rate of parasites.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 402-50-6. Formula: C9H7F3.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 402-50-6 is helpful to your research. Name: 1-(Trifluoromethyl)-4-vinylbenzene.

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Name: 1-(Trifluoromethyl)-4-vinylbenzene, 402-50-6, Name is 1-(Trifluoromethyl)-4-vinylbenzene, SMILES is FC(F)(F)C1=CC=C(C=C)C=C1, belongs to phthalazine compound. In a document, author is Goli-Jolodar, Omid, introduce the new discover.

Introduction of a Novel Nano Sized N-Sulfonated Bronsted Acidic Homogeneous Catalyst for the Promotion of the Synthesis of 2H-Indazolo[2,1-b] Phthalazine-1,6,11(13H)-Triones

In this research work, 4,4′-(butane-1,4-diyl) bis(1-sulfo-1,4-diazabicyclo[2.2.2]octane-1,4-diium) tetrachloride (NS-C4(DABCO-SO3H)(2)center dot 4Cl) as a new nano-sized N-sulfonic acid was prepared and characterized using different types of spectroscopic methods including FT-IR, H-1 NMR, C-13 NMR, XRD, TGA and SEM analysis. This new reagent was efficiently used as catalyst for the promotion of the one-pot synthesis of 2H-indazolo[2,1-b] phthalazine-1,6,11(13H)-triones derivatives, as a class of biologically active compounds with important pharmaceutical properties, under solvent-free conditions during short reaction times in high yields.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 402-50-6 is helpful to your research. Name: 1-(Trifluoromethyl)-4-vinylbenzene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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If you are interested in 402-50-6, you can contact me at any time and look forward to more communication. Computed Properties of C9H7F3.

In an article, author is Esmaeilpour, Mohsen, once mentioned the application of 402-50-6, Computed Properties of C9H7F3, Name is 1-(Trifluoromethyl)-4-vinylbenzene, molecular formula is C9H7F3, molecular weight is 172.1471, MDL number is MFCD00075539, category is phthalazines. Now introduce a scientific discovery about this category.

Preparation, characterization and catalytic activity of dendrimer-encapsulated phosphotungstic acid nanoparticles immobilized on nanosilica for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones under solvent-free or sonochemical conditions

In this paper, we adopt a facile method to prepare a type of porous silica nanoparticles (n-SiO2) from tetraethyl orthosilicate as the source of silica. Then, dendritic polymer supported on nanosilica with surface amino groups was fabricated. Finally, H3PW12O40 nanoparticles (PWA(n)) were synthesized by the treatment of H3PW12O40 powder with n-Octane as solvent by a solvothermal method and then immobilized onto the dendrimer polymer functionalized nanosilica. The synthesized nanostructures were characterized by fourier transform infrared (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), dynamic light scattering (DLS), N-2 adsorption-desorption isotherm analysis, UV-Vis and elemental analysis. The morphology of the catalyst was characterized using transmission electron microscopes (TEM). The acidity of the catalyst was determined by FTIR pyridine adsorption spectroscopy. Then, this catalytic system was used as an efficient catalyst for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones via multi-component and one-pot reactions of various aldehydes, phthalic anhydride, hydrazinium hydroxide, and dimedone under thermal solvent-free conditions or ultrasound irradiation at room temperature. Also, the catalyst can be easily recovered and reused for six consecutive reaction cycles without significant loss of activity.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

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We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 402-50-6. The above is the message from the blog manager. Safety of 1-(Trifluoromethyl)-4-vinylbenzene.

402-50-6, Name is 1-(Trifluoromethyl)-4-vinylbenzene, molecular formula is C9H7F3, belongs to phthalazines compound, is a common compound. In a patnet, author is Huang, Shengyun, once mentioned the new application about 402-50-6, Safety of 1-(Trifluoromethyl)-4-vinylbenzene.

Study of aldehyde oxidase with phthalazine as substrate using both off-line and on-line capillary electrophoresis

An optimized and economical capillary electrophoretic method for both off-line and on-line study of the enzyme aldehyde oxidase and its substrate phthalazine was developed. The separation of the substrate phthalazine and its metabolite 1-phthalazinone was achieved using micellar electrokinetic chromatography (MEKC) with sodium dodecyl sulphate in the background electrolyte (BGE). The BGE consists of 25 mM sodium phosphate buffer containing 50 mM sodium dodecyl sulphate at pH 7.4. A bare-fused-silica capillary with a capillary length of 40 cm, 50 mu m ID and effective length of 30 cm was used to develop the capillary electrophoresis method. Improved separation conditions were elaborated and the separation method was validated based on the ICH and EMA guidelines. The limit of detection for phthalazine and 1-phthalazinone was 8 mu M and 3 mu M, respectively. The limit of quantification was 25 mu M for phthalazine and 10 mu M for 1-phthalazinone. The linearity of the detector response was checked for 1-phthalazinone at nine different concentrations in the range 10-500 mu M and the determination coefficient was 0.9994. Accuracy was tested by comparing the corrected peak area of 1-phthalazinone reference solution at 20 mu M and 50 mu M with the corrected peak area of 20 mu M and 50 mu M 1-phthalazinone in the presence of human liver cytosol (HLC). Accuracy values of +5.3% and -2.5% were obtained at 20 mu M and 50 mu M, respectively. The on-line enzymatic reaction was successful with the application of the method of transverse diffusion of laminar flow profiles (TDLFP), which enables the mixing as well as separation of the enzyme and substrate inside the nanoliter-scale capillary. TDLFP is examined to be precise when performing 5 consecutive injections, with a relative standard deviation of 7.16% which is within the limitation of EMA standards. This miniaturized and low-cost incubation and separation method could be further introduced into industry and extended to other substrates. (C) 2018 Elsevier B.V. All rights reserved.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 402-50-6. The above is the message from the blog manager. Safety of 1-(Trifluoromethyl)-4-vinylbenzene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Some scientific research about 1-(Trifluoromethyl)-4-vinylbenzene

Interested yet? Read on for other articles about 402-50-6, you can contact me at any time and look forward to more communication. Name: 1-(Trifluoromethyl)-4-vinylbenzene.

Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 402-50-6, Name is 1-(Trifluoromethyl)-4-vinylbenzene, SMILES is FC(F)(F)C1=CC=C(C=C)C=C1, in an article , author is Dam, Binoyargha, once mentioned of 402-50-6, Name: 1-(Trifluoromethyl)-4-vinylbenzene.

Nano-ferrite supported glutathione as a reusable nano-organocatalyst for the synthesis of phthalazine-trione and dione derivatives under solvent-free conditions

Nano-organocatalyzed one-pot four-component reactions for the synthesis of phthalazine-trione/dione derivatives have been devised for the first time from easily accessible starting materials under solvent-free conditions. This methodology showed very good substrate scope and high degree of tolerance for a variety of aldehydes (including aliphatic and heteroaromatic aldehydes) and active methylene compounds. Moreover, the catalyst can be easily separated from the reaction mixture because of its highly paramagnetic nature, by using an external magnet, and can be reused in five more consecutive runs without much decrease in catalytic activities. Other significant advantages of this method are shorter reaction time, good yield, simple work-up procedure, easy catalyst handling etc.

Interested yet? Read on for other articles about 402-50-6, you can contact me at any time and look forward to more communication. Name: 1-(Trifluoromethyl)-4-vinylbenzene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Top Picks: new discover of C9H7F3

Interested yet? Keep reading other articles of 402-50-6, you can contact me at any time and look forward to more communication. Quality Control of 1-(Trifluoromethyl)-4-vinylbenzene.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 402-50-6, Name is 1-(Trifluoromethyl)-4-vinylbenzene, molecular formula is C9H7F3. In an article, author is Wang Yinglei,once mentioned of 402-50-6, Quality Control of 1-(Trifluoromethyl)-4-vinylbenzene.

Synthesis of Pyrazolo[1,2-b]phthalazine-5,10-diones Catalyzed by Poly(ethylene glycol) Grafted 4-Dimethylaminopyridine Functionalized Ionic Liquid

A novel poly(ethylene glycol) grafted 4-dimethylaminopyridine functionalized ionic liquid ([DMAP-PEG(1000)-DIL][BF4]) was prepared and characterized by H-1 NMR, C-13 NMR, FT-IR and ESI-MS. In the presence of [DMAP-PEG(1000)-DIL][BE4], various substituted aromatic aldehyde could react with malononitrile (or ethyl cyanoacetate) and phthalhydrazide in water to obtain a series of pyrazolo[1,2-b]phthalazine-5,10-dione derivatives with 85%similar to 96% yields. The mild reaction conditions, high stable and recyclable ionic liquids, environmental friendliness are advantages of this methodology.

Interested yet? Keep reading other articles of 402-50-6, you can contact me at any time and look forward to more communication. Quality Control of 1-(Trifluoromethyl)-4-vinylbenzene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Never Underestimate The Influence Of 1-(Trifluoromethyl)-4-vinylbenzene

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 402-50-6 is helpful to your research. Name: 1-(Trifluoromethyl)-4-vinylbenzene.

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 402-50-6, Name is 1-(Trifluoromethyl)-4-vinylbenzene, SMILES is FC(F)(F)C1=CC=C(C=C)C=C1, belongs to phthalazines compound. In a document, author is Mirahmadpour, Pari, introduce the new discover, Name: 1-(Trifluoromethyl)-4-vinylbenzene.

Electrochemical Oxidation of 2,3-dihydrophthalazine-1,4-dione in the Presence of Indole Derivatives

The electrochemical oxidation of 2,3-dihydrophthalazine-1,4-dione (1) has been studied in the presence of indole derivatives as nucleophiles in a water/acetonitrile mixture by means of cyclic voltammetry and controlled-potential coulometry. Results indicate that electrogenerated phthalazine-1,4-dione (1ox) participates in a Michael type addition reaction with indole derivatives (2 and 3) via an EC mechanism. In this work, we propose a mechanism for the electrode process. The electrochemical synthesis of indoylphthalazines (4 and 5) has been successfully performed at a carbon rod electrode and in an undivided cell. (C) 2013 The Electrochemical Society. All rights reserved.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 402-50-6 is helpful to your research. Name: 1-(Trifluoromethyl)-4-vinylbenzene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem