Category: 523-27-3

You could be based in a university, combining chemical research with teaching; in a pharmaceutical company, working on developing and trialing new drugs; helping to ensure national healthcare provision keeps pace with new discoveries. 523-27-3, Name is 9,10-Dibromoanthracene, SMILES is BrC1=C2C=CC=CC2=C(Br)C3=CC=CC=C13, belongs to phthalazine compound. In a document, author is Hamidinasab, Mahdia, introduce the new discover, Application In Synthesis of 9,10-Dibromoanthracene.

The catalytic activity of four heterogeneous solid acid catalysts with magnetic core and sulfonic acid groups is evaluated and compared using one-pot three component synthesis of phthalazine-trione derivatives under solvent-free condition. The NiFe2O4 particles were selected as magnetic core, due to their enhanced chemical and magnetic stability. Furthermore, the desired products were obtained in excellent yields at short reaction times and environmentally friendly condition using the novel and reusable sulfonic acid grafted onto TiO2-coated nickel ferrite nanoparticles. This protocol avoids the use of expensive catalysts, toxic solvents and harsh reaction conditions.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 523-27-3. Application In Synthesis of 9,10-Dibromoanthracene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Product Details of 523-27-3, Career opportunities within science and technology are seeing unprecedented growth across the world, and those who study chemistry or another natural science at university now have increasingly better career prospects. 523-27-3, Name is 9,10-Dibromoanthracene, SMILES is BrC1=C2C=CC=CC2=C(Br)C3=CC=CC=C13, belongs to phthalazine compound. In a article, author is Raghuvanshi, Dushyant Singh, introduce new discover of the category.

A high yielding and environmentally benign synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives has been achieved using silica-supported KHSO4 catalyst under solvent-free conditions. The methodology adopted is simple, versatile and requires no column chromatography.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 523-27-3 help many people in the next few years. Product Details of 523-27-3.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

With the volume and accessibility of scientific research increasing across the world, it has never been more important to continue building the reputation for quality and ethical publishing we’ve spent the past two centuries establishing. 523-27-3, Name is 9,10-Dibromoanthracene, SMILES is BrC1=C2C=CC=CC2=C(Br)C3=CC=CC=C13, in an article , author is Wedek, Volker, once mentioned of 523-27-3, Application In Synthesis of 9,10-Dibromoanthracene.

The use of a new class of unsymmetrical cinchona-alkaloid-based, phthalazine-bridged organocatalysts enabled the highly enantioselective dichlorination of unfunctionalized alkenes. In combination with the electrophilic chlorinating agent 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) and triethylsilyl chloride (TES-Cl) as the source of nucleophilic chloride, 1-aryl-2-alkyl alkenes were dichlorinated with enantioselectivities of up to 94:6 er. Initial mechanistic investigations suggest that no free chlorine is formed, and by replacement of the chloride by fluoride, enantioselective chlorofluorinations of alkenes are possible.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 523-27-3, you can contact me at any time and look forward to more communication. Application In Synthesis of 9,10-Dibromoanthracene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Related Products of 523-27-3, Academic researchers, R&D teams, teachers, students, policy makers and the media all rely on us to share knowledge that is reliable, accurate and cutting-edge. 523-27-3, Name is 9,10-Dibromoanthracene, SMILES is BrC1=C2C=CC=CC2=C(Br)C3=CC=CC=C13, belongs to phthalazine compound. In a article, author is Dong, Yong Ping, introduce new discover of the category.

Chemiluminescence (CL) of a cyclometallated iridium (III) complex {tris[1-(2,6-dimethylphenoxy)-4-(4-chlorophenyl)phthalazine]iridium(III)} in the presence of potassium permanganate and oxalic acid is reported for the first time. Cysteine exhibits sufficient enhancing effect on the CL generated from the cyclometallated iridium(III) complex, which make it possible for the sensitive detection of cysteine using a flow-injectionchemiluminescence (FICL) method. The optimum conditions for the chemiluminescence emission were investigated. Under the optimal condition, the linear range for the determination of cysteine was 1.0?x?1095.0?x?106?mol/L with a detection limit of 6.9?x?1010?mol/L. A relative standard deviation of 1.6% was obtained for eight replicate determinations. The mechanisms of CL are proposed and the emitting species was identified as the metal-to-ligand charge-transfer (MLCT) excited states of the iridium complex. Copyright (c) 2011 John Wiley & Sons, Ltd.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemical research careers are more diverse than they might first appear, as there are many different reasons to conduct research and many possible environments. , Category: phthalazines, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 523-27-3, Name is 9,10-Dibromoanthracene, molecular formula is C14H8Br2, belongs to phthalazine compound. In a document, author is El-Helby, Abdel-Ghany A..

In view of the anticonvulsant activity reported for phthalazine derivatives as non-competitive AMPA receptor antagonists, a new series of phthalazine-1,4-diones (2-12) were designed and synthesized. The neurotoxicity was assessed using rotarod test. The molecular docking was performed for the synthesized compounds to assess their binding affinities toward AMPA receptor as non-competitive antagonists. The molecular modeling data were strongly interrelated to biological screening data. Compounds 8, 7(b), 7(a), 10 and 3(a) exhibited the highest binding affinities as non-competitive AMPA receptor antagonists and also showed the highest relative potencies of 1.78, 1.66, 1.60, 1.59 and 1.29, respectively, as anticonvulsants in comparison with diazepam. The most active compounds 8, 7(b), 7(a), 10 and 3(a) were further tested against maximal electroshock seizure (MES). Compounds 8 and 7(b) and 3(a) showed 100% protection at a dose level of 125 mu gm/kg, while compounds 7(a) and 10 exhibited 83.33% protection at the same dose level. These agents exerted low neurotoxicity and high safety margin in comparison with valproate as a reference drug. Most of our designed compounds exhibited good ADMET profile.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Safety of 9,10-Dibromoanthracene, We’ll be discussing some of the latest developments in chemical about CAS: 523-27-3, Name is 9,10-Dibromoanthracene, SMILES is BrC1=C2C=CC=CC2=C(Br)C3=CC=CC=C13, belongs to phthalazine compound. In a article, author is Chen, Hui, introduce new discover of the category.

An efficient one-pot synthesis of spiro[indoline-3,1′-pyrazolo[1,2-b]phthalazine] derivatives via three-component reaction of phthalhydrazide, isatin, and malononitrile (cyanoacetic ester) is described. This new protocol has the advantages of high efficiency, mild reaction conditions, one-pot procedure, and convenient operation.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 523-27-3. Product Details of 523-27-3.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Safety of 9,10-Dibromoanthracene, While the job of a research scientist varies, most chemistry careers in research are based in laboratories, where research is conducted by teams following scientific methods and standards. 523-27-3, Name is 9,10-Dibromoanthracene, SMILES is BrC1=C2C=CC=CC2=C(Br)C3=CC=CC=C13, belongs to phthalazine compound. In a article, author is Chavan, Laxmikant D., introduce new discover of the category.

A series of 11-molybdo-1-vanadophosphoric acid supported on montmorillonite K-10 catalysts were prepared and characterized by FT-IR spectroscopy, thermal analysis, XRD, BET and SEM analysis techniques. Characterization data reveals the chemical immobilization of H4PMo11V1O40 catalyst on the montmorillonite K-10 support. The catalytic performance of synthesized catalysts was investigated for the synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives by one-pot three-component reaction of phthalhydrazide, dimedone and aromatic aldehydes under solvent-free conditions. Among different catalysts, 20% H4PMo11V1O40 supported on to montmorillonite K-10 showed the highest catalytic activity. Effect of reaction parameters such as catalyst loading, temperature and the nature of substituents on the aromatic ring of aldehydes were also evaluated. The protocol developed using H4PMo11V1O40/K-10 has several distinct advantages such as operational simplicity, short reaction time, high yield, reusable catalyst and preclusion of toxic solvent.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 523-27-3 help many people in the next few years. Safety of 9,10-Dibromoanthracene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Reference of 523-27-3, Career opportunities within science and technology are seeing unprecedented growth across the world, and those who study chemistry or another natural science at university now have increasingly better career prospects. 523-27-3, Name is 9,10-Dibromoanthracene, SMILES is BrC1=C2C=CC=CC2=C(Br)C3=CC=CC=C13, belongs to phthalazine compound. In a article, author is Mohamadpour, Farzaneh, introduce new discover of the category.

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) as a highly efficient bicyclic amidine catalyst promoted one-pot multi-component synthesis of biologically active 1H-pyrazolo [1, 2-b] phthalazine-5, 10-dione derivatives via one-pot four-component condensation reaction of phthalimide, hydrazine monohydrate, aryl aldehydes and malononitrile under solvent-free conditions through simple filter with no necessity of chromatographic purification steps. Use of safe, non-volatile, non-corrosive, highly efficient, readily available and easy to handle of catalyst, one-pot reaction, high yields and short reaction times, economical and convenient synthesis, solvent-free conditions and operational simplicity are among the other added advantages that make this approach an attractive alternative for the synthesis of these biologically active compounds.

Reference of 523-27-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 523-27-3 is helpful to your research.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. HPLC of Formula: https://www.ambeed.com/products/523-27-3.html, 523-27-3, Name is 9,10-Dibromoanthracene, SMILES is BrC1=C2C=CC=CC2=C(Br)C3=CC=CC=C13, in an article , author is Ibrahim, Hany S., once mentioned of 523-27-3.

RAB1 5 is a lead antibacterial agent in which trimethoprim is linked to phthalazine moiety. Similarly, our strategy in this research depends on the interconnection between some sulfa drugs and certain phthalazin-1(2H)-one scaffolds in an attempt to enhance their antibacterial activity. This approach was achieved through the combination of 4-substituted phthalazin-1(2H)-ones 9a, b or 14a, b with sulfanilamide 1a, sulfathiazole 1b or sulfadiazine 1c through amide linkers 6a, b to produce the target compounds 10a-d and 15a-e, respectively. The antibacterial activity of the newly synthesized compounds showed that all tested compounds have antibacterial activity higher than that of their reference sulfa drugs 1a-c. Compound 10c represented the highest antibacterial activity against Gram-positive bacteria Streptococcus pneumonia and Staphylococcus aureus with MIC = 0.39 mu mol/mL. Moreover, compound 10d displayed excellent antibacterial activity against Gram-negative bacteria Escherichia coli and Salmonella Lyphimurium with MIC = 0.39 and 0.78 mu mol/mL, respectively. (C) 2014 Elsevier Masson SAS. All rights reserved.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 523-27-3, you can contact me at any time and look forward to more communication. HPLC of Formula: https://www.ambeed.com/products/523-27-3.html.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Researchers are common within chemical engineering and are often tasked with creating and developing new chemical techniques, frequently combining other advanced and emerging scientific areas. Quality Control of 9,10-Dibromoanthracene, 523-27-3, Name is 9,10-Dibromoanthracene, SMILES is BrC1=C2C=CC=CC2=C(Br)C3=CC=CC=C13, in an article , author is Shirini, Farhad, once mentioned of 523-27-3.

1,4-Disulfo-1,4-diazabicyclo[2.2.2]octane-1,4-diium dihydrogen sulfate {DABCO(HSO3)(2)(HSO4)(2)} as a new ionic liquid, is prepared and characterized by using different methods including FT-IR, NMR, Mass and SEM analysis as well as determination of the Hammett acidity function. This reagent can be used as an efficient catalyst for the promotion of the synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives as important biologically active compounds with pharmaceutical properties. All reactions are performed in the absence of solvent using small amounts of the catalyst. Easy preparation of the catalyst, simple and easy work-up, mild reaction conditions, green process, excellent yields and short reaction times are the most important advantages this of method. (C) 2015 Elsevier Ltd. All rights reserved.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 523-27-3. Quality Control of 9,10-Dibromoanthracene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem