Category: 622-95-7

Related Products of 622-95-7, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 622-95-7, Name is 1-(Bromomethyl)-4-chlorobenzene, SMILES is ClC1=CC=C(CBr)C=C1, belongs to phthalazines compound. In a article, author is Chacko, Priya, introduce new discover of the category.

Nano Structured Bi2O3 Catalyzed Synthesis of 3-Phenyl-[1,2,4]Triazolo[3,4-a]Phthalazines and Their Cross-coupling Reaction Under Aqueous Conditions

A novel and an expeditious approach for the synthesis of 3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine derivatives has been achieved from 1,4-dichlorophthlazine and benzohydrazides in the presence of nano Bi2O3 catalyst. 3-Phenyl-[1,2,4]triazolo[3,4-a]phthalazines undergo substitution reaction with various -OH group to produce 6-substituted-3-phenyl-[1,2,4]triazolo[3,4-a]phthalazines in excellent yields under aqueous condition in the presence of Pd(OAc)(2), BINAP and nano Bi2O3 catalyst. The present protocol tolerates various functional groups and represents a reliable and time efficient method.

Related Products of 622-95-7, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 622-95-7.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

In an article, author is Wang, Shi-Ben, once mentioned the application of 622-95-7, Safety of 1-(Bromomethyl)-4-chlorobenzene, Name is 1-(Bromomethyl)-4-chlorobenzene, molecular formula is C7H6BrCl, molecular weight is 205.4795, MDL number is MFCD00040714, category is phthalazines. Now introduce a scientific discovery about this category.

Synthesis and Anticonvulsant Activity Evaluation of Some 1-alkoxy-4-(1H-1,2,4-triazol-1-yl)phthalazines

A series of 1-alkoxy-4-(1H-1,2,4-triazol-1-yl)phthalazine derivatives were synthesized using 2,3-dihydrophthalazine-1,4-dione as starting material. The structures of the compounds were characterized by elemental analysis, IR, H-1-NMR and MS data. Anticonvulsant activities of these compounds were evaluated by maximal electroshock (MES) test following intraperitoneal injection in mice. Among the synthesized compounds 3a-3t, compound 3e was the most active compound with an ED50 of 28.9 mg/kg, TD50 of 173.6 mg/kg and protective index (PI) of 6.0.

If you are interested in 622-95-7, you can contact me at any time and look forward to more communication. Safety of 1-(Bromomethyl)-4-chlorobenzene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem