Tag: M.W:100-200

Synthetic Route of 643-79-8, Academic researchers, R&D teams, teachers, students, policy makers and the media all rely on us to share knowledge that is reliable, accurate and cutting-edge. 643-79-8, Name is Benzene-1,2-dicarboxaldehyde, SMILES is O=CC1=CC=CC=C1C=O, belongs to phthalazine compound. In a article, author is Mazaahir, Kidwai, introduce new discover of the category.

A convenient, economical and green approach to the synthesis of 1H-indazolo[1,2-b]phthalazine-1,6,11-trione derivatives has been achieved via a one-pot protocol using phthalhydrazide, a cyclic-beta-diketone and an aldehyde in the presence of a ceric ammonium nitrate catalyst in polyethylene glycol. The simple work up, mild conditions, excellent yields, inexpensive and non-toxic catalyst and simple solvent recyclability render this protocol both attractive and economically viable.

Synthetic Route of 643-79-8, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 643-79-8 is helpful to your research.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Recommanded Product: 613-45-6, Academic researchers, R&D teams, teachers, students, policy makers and the media all rely on us to share knowledge that is reliable, accurate and cutting-edge. 613-45-6, Name is 2,4-Dimethoxybenzaldehyde, SMILES is O=CC1=CC=C(OC)C=C1OC, belongs to phthalazine compound. In a article, author is Rizk, Sameh A., introduce new discover of the category.

Phthalazines have received considerable attention for their wide antimicrobial activity. Regiospecific nucleophilic attack of 4-benzylphthalazin-1-ol by the 1-oxo rather than the aza group on different alkyl halides gave novel phthalazine heterocyclic derivatives. Moreover, a variety of nucleosides bonded to electron-withdrawing groups were synthesized using 4-benzylphthalazine-1-ol. The density functional theory has been used to investigate the electronic structure of the synthesized compounds. All of the synthesized derivatives showed remarkable activity when tested against Gram-positive and Gram-negative bacteria, Aspergillus niger, and Candida albicans. The reactivity of these nucleosides was expected to arise from their bonding with the lone pair of N-atom of the macromolecules of bacteria. These bonding were expected to inhibit the enzyme by forming highly stable complex with lower highest occupied molecular orbital energy. The structures of these synthesized derivatives were established by Fourier transform infrared, H-1-NMR, and C-13-NMR spectroscopic evidence.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

HPLC of Formula: https://www.ambeed.com/products/41263-74-5.html, Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. 41263-74-5, Name is 4-(Methylamino)-3-nitrobenzoic acid, SMILES is O=C(O)C1=CC=C(NC)C([N+]([O-])=O)=C1, belongs to phthalazine compound. In a article, author is Popov, L. D., introduce new discover of the category.

Structure of copper(II) chelates based on glyoxylic hetarylhydrazones containing benzazole (quinoxaline and phthalazine) fragments have been studied by EPR spectroscopy. Spectral parameters in polycrystalline state and dimethylformamide solutions have been determined. Spectral parameters of benzimidazole derivative are typical for square planar structure of the chelate node, while phthalazine derivative displays formation of polymeric structures due to reduction of copper(II) atom.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 41263-74-5, you can contact me at any time and look forward to more communication. HPLC of Formula: https://www.ambeed.com/products/41263-74-5.html.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. In an article, author is Kour, Manmeet, once mentioned the application of 767-00-0, Name is 4-Hydroxybenzonitrile, molecular formula is C7H5NO, molecular weight is 119.12, MDL number is MFCD00002312, category is phthalazine. Now introduce a scientific discovery about this category, Application of 767-00-0.

A highly active and stable ionic liquid based novel solid Bronsted acid catalyst (C@TiO2-SO3H-ILs) was prepared by coating a long chain ionic liquid onto sulfonated carbon@titania composites. The ionic liquid coating resulted in efficient stability and activity of C@TiO2-SO3H-ILs under aqueous conditions by creating a hydrophobic environment on the catalyst surface. The catalytic activity of the newly designed catalyst was tested in the one-pot multicomponent synthesis of indeno[1,2-b]indole-9,10-diones and 1H-pyrazolo[1,2-b]phthalazine-5,10-diones in aqueous media. The structure of the most active catalyst, C@TiO2-SO3H-IL1, before and after the coating with the ionic liquid was investigated by FTIR, TGA, XRD, CHNS, EDX, SEM and HRTEM. The catalyst allows easy recovery and excellent reusability for up to five catalytic runs without considerable loss of activity.

Application of 767-00-0, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 767-00-0.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Application of 103-45-7, In classical electrochemical theory, both the electron transfer rate and the adsorption of reactants at the electrode control the electrochemical reaction. 103-45-7, Name is Phenethyl acetate, SMILES is CC(OCCC1=CC=CC=C1)=O, belongs to phthalazine compound. In a article, author is Gan, Min, introduce new discover of the category.

Amino-acid-derived phthalazine catalysts have been designed and synthesized for enantioselective halolactonization of prochiral dienoic acids. The scope of the reaction is evidenced by 17 examples of Spiro a-exo-methylene-halolactones with up to 99.8% enantiomeric excess. The resulting enantio-enriched Spiro halolactone products are found to exhibit potent antitumor effects. In addition, both antipodes of products with equally excellent enantioselevity could be obtained since a pair of enantiomeric catalysts is guaranteed.

Application of 103-45-7, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 103-45-7.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Electric Literature of 103-45-7, Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition. 103-45-7, Name is Phenethyl acetate, SMILES is CC(OCCC1=CC=CC=C1)=O, belongs to phthalazine compound. In a article, author is Afzalian, Behnaz, introduce new discover of the category.

Three complexes containing 2-pyrazinecarboxylate (pzca(-)), including [Ni(pzca)(2)(H2O)(2)], [Co(pzca)(2)(H2O)(2)], and [Cu(pzca)(2)(H2O)(2)], have been synthesized and characterized using physicochemical and spectroscopic methods. Furthermore, the structure of each complex was determined by single-crystal X-ray diffraction. All three complexes have an octahedral geometry, where the metal ion chelated by two carboxylate oxygens, two nitrogen atoms belonging to pyrazinic acid molecules, and two oxygen atoms of two water molecules. The catalytic activities of these complexes were also investigated in the green synthesis of 2H-indazolo[2,1-b]phthalazine-triones by the reaction of hydrazine hydrate with an arylaldehyde, phthalic anhydride, and dimedone in acetic acid. (C) 2015, Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

Electric Literature of 103-45-7, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 103-45-7 is helpful to your research.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Recommanded Product: 140-75-0, We’ll be discussing some of the latest developments in chemical about CAS: 140-75-0, Name is (4-Fluorophenyl)methanamine, SMILES is C1=C(C=CC(=C1)F)CN, belongs to phthalazine compound. In a article, author is Kidwai, Mazaahir, introduce new discover of the category.

A new green protocol has been developed for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones via one-pot, three-component condensation reaction of aromatic aldehydes with 1,3-dicarbonyl compounds and phthalhydrazide using reusable dodecylphosphonic acid (DPA) as heterogeneous solid acid catalyst under solvent-free conditions. This protocol provides a novel and improved method for obtaining 2H-indazolo[2,1-b]phthalazine-triones in terms of good yields with little catalyst loading. (C) 2012 Elsevier Ltd. All rights reserved.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

You could be based in a university, combining chemical research with teaching; in a pharmaceutical company, working on developing and trialing new drugs; helping to ensure national healthcare provision keeps pace with new discoveries. 89-86-1, Name is 2,4-Dihydroxybenzoic acid, SMILES is O=C(O)C1=CC=C(O)C=C1O, belongs to phthalazine compound. In a document, author is Yunta, Maria J. R., introduce the new discover, COA of Formula: https://www.ambeed.com/products/89-86-1.html.

Computational techniques are widely used to reduce costs associated with new drug development with the ability to bind a specific molecular target. These studies need a Brookhaven protein data bank structure sample of the enzyme interaction with an inhibitor of adequate size. In this context, a new computational methodology is postulated to be used when there are no published samples fulfilling this requirements. In this study, 7 compounds, which showed anti-T. cruzi, L. donovani and L. infantum properties, and proved to be inhibitors of their Fe-SOD enzymes, have been theoretically evaluated against related parasites Fe-SOD enzymes, which have been proposed as targets for antiparasitic drugs. This methodology may be applied to similar cases and also to generate starting structures to be used with different CADD methods

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 89-86-1, in my other articles. COA of Formula: https://www.ambeed.com/products/89-86-1.html.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

You could be based in a university, combining chemical research with teaching; in a pharmaceutical company, working on developing and trialing new drugs; helping to ensure national healthcare provision keeps pace with new discoveries. 1679-64-7, Name is 4-(Methoxycarbonyl)benzoic acid, SMILES is C1=CC(=CC=C1C(O)=O)C(OC)=O, belongs to phthalazine compound. In a document, author is Maleki, Behrooz, introduce the new discover, Reference of 1679-64-7.

A novel nanomagnetic basic catalyst of caesium carbonate supported on hydroxyapatite-coated Ni0.5Zn0.5Fe2O4 magnetic nanoparticles (Ni0.5Zn0.5Fe2O4@HAP-Cs2CO3) was prepared. This new catalyst was fully characterized using Fourier transform infrared spectroscopy, transmission and scanning electron microscopy, X-ray diffraction and vibrating sample magnetometry techniques, and then the catalytic activity of this catalyst was investigated in the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives. Also, Ni0.5Zn0.5Fe2O4@HAP-Cs2CO3 could be reused at least five times without significant loss of activity and could be recovered easily by applying an external magnet. Thus, the developed nanomagnetic catalyst is potentially useful for the green and economic production of organic compounds. Copyright (c) 2015 John Wiley & Sons, Ltd.

Reference of 1679-64-7, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1679-64-7.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Product Details of 139-66-2, Career opportunities within science and technology are seeing unprecedented growth across the world, and those who study chemistry or another natural science at university now have increasingly better career prospects. 139-66-2, Name is Diphenylsulfane, SMILES is C1(SC2=CC=CC=C2)=CC=CC=C1, belongs to phthalazine compound. In a article, author is Mourad, Asmaa Kamal, introduce new discover of the category.

Phthalazine and phthalazinone derivatives are important owing to their significant biological activities and pharmacological properties. Herein, a benzoic acid derivative (2), a benzoxazin-1-one derivative (3), and an oxophthalazin-2(1H)-yl)acetohydrazide (13) are utilized as precursors to construct a novel series of phthalazinones bearing various valuable functional groups in excellent yields via several simple and promising approaches. Finally, the antimicrobial activity of the newly synthesized phthalazines is screened against different microbial strains; namely, Gram-negative and Gram-positive bacteria utilizing Amoxicillin as a standard drug.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 139-66-2, you can contact me at any time and look forward to more communication. Product Details of 139-66-2.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem