Tag: M.W:100-200

Application of 5267-64-1, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 5267-64-1, Name is D-Penylalaninol, SMILES is OC[C@H](N)CC1=CC=CC=C1, belongs to phthalazine compound. In a article, author is Ramezani, Mahin, introduce new discover of the category.

In this paper we investigated reactions of urazole and phthalazine with N-(aryl)-2,2,2-trifluoroacetimidoyl chloride derivatives. Results showed that when imidoyl chloride derivative has a fluorine atom at ortho position (3a-c), in two steps under a S(N)i mechanism and then SNAr reaction mechanism produce ay1-5-(trifluoromethyl)-1H-benzo [el [1,2,4]triazolo[1,2-a] [1,2,4]triazine-1,3(2H)-diones (4a-c) and 6-(trifluoromethyl)benzo[5,6][1,2,4]triazino[1,2-b]phthalazine-8,13-diones (4i,4j) in good to excellent yields. In the other imidoyl derivatives (3d-h and 3i,3j) under these conditions cyclization reaction does not occur and therefore produce 1-aryl-2,2,2-trifluorornethyl)-4-phenyl-1,2,4-triazolidine-3,5-diones (4d-h) and 2-(2,2,2-trifluoro-1-(arylimino)ethyl)-2,3-dihydrophthalazine-1,4-diones(4k,41) (non-cyclic products) in good to excellent yields. (C) 2016 Elsevier B.V. All rights reserved.

Application of 5267-64-1, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 5267-64-1.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Product Details of 613-45-6, 613-45-6, Name is 2,4-Dimethoxybenzaldehyde, SMILES is O=CC1=CC=C(OC)C=C1OC, in an article , author is Turhan, K., once mentioned of 613-45-6.

In this study, substituted 2H-indazolo[2,1-b]phthalazine-1,6,11-triones, that may possess biological activity, have been synthesized via one-pot three-component cyclocondensation reaction of aromatic aldehydes, cyclic 1,3-dione and phthalhydrazide in ethanol catalyzed by Y(OTf)(3) with good to excellent yields. The structures of all synthesized compounds, 3,4-dihydro-13-phenyl-2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione (4a), 13-(4-cyanophenyl)-3,4-dihydro-2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione (4b), 3,4-dihydro-3,3-dimethyl-13-(4-cyanophenyl)-2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione (4c), 3,4-dihydro-3,3-dimethyl-13-phenyl-2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione (4d), and 3,4-dihydro-13-(4-isopropylphenyl)-3,3-dimethyl-2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione (4e) have been elucidated from IR, NMR and mass spectral data.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 613-45-6, you can contact me at any time and look forward to more communication. Product Details of 613-45-6.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: α,α’-Dichloro-p-xylene, 623-25-6, Name is α,α’-Dichloro-p-xylene, SMILES is ClCC1=CC=C(CCl)C=C1, belongs to phthalazine compound. In a document, author is Sherif, Yousery E., introduce the new discover.

1,4-Dioxo-3, 4, 4e, 5, 10, 10a-hexahydro-1H-5,10-benzenobenzo [g] phthalazin-2-yl-thioamide [6a]; 1,4-dioxo-3, 4, 4e, 5, 10, 10a-hexahydro-1H-5, 10-benzenobenzo [g] phthalazin-2-yl-N-pyridylthioamide [6b] and 1,4-dioxo-3, 4, 4e, 5, 10, 10a-hexahydro-1H-5, 10-benzenobenzo[g]phthalazin-2-yl-N-ethylthioamide [6c] and their [Cu(6a-H)(OAc)], [Zn(6a-H)(OAc)], [Cu(6b-H)(H2O)(2)(OAc)]center dot 3H(2)O and [Zn(6b-H)(OAc)], [Cu-2(6c-H)](OAc)(3)]center dot 2H(2)O and [Zn(6c-H)(OAc)] complexes have been synthesized via a reaction between phthalazinedione 6a-c derivatives and the acetate salt of Cu(II) or Zn(II). These compounds were characterized by elemental analysis, spectra (UV-Vis, IR, H-1 NMR, C-13 NMR, ESR), conductance, thermal analysis and magnetic moments.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 623-25-6. Recommanded Product: α,α’-Dichloro-p-xylene.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry, like all the natural sciences, HPLC of Formula: https://www.ambeed.com/products/371-42-6.html, begins with the direct observation of nature— in this case, of matter.371-42-6, Name is 4-Fluorothiophenol, SMILES is SC1=CC=C(F)C=C1, belongs to phthalazine compound. In a document, author is Lashkari, Mojtaba, introduce the new discover.

A simple synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives via one-pot four-component condensation reaction of phthalimide, hydrazine monohydrate, aromatic aldehyde derivatives and malononitrile in the presence of a catalytic amount of zirconium tetrachloride (ZrCl4) as a mild and efficient Lewis acidic catalyst under thermal and solvent-free conditions with good yields and short reaction times is developed. This present methodology has notable benefits such as high efficiency, inexpensive and non-toxic catalyst, environmentally benign nature, solvent-free conditions and simplicity of operation.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 371-42-6. HPLC of Formula: https://www.ambeed.com/products/371-42-6.html.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 104-53-0, Name is 3-Phenylpropanal, molecular formula is C9H10O. In an article, author is Behalo, Mohamed S.,once mentioned of 104-53-0, COA of Formula: https://www.ambeed.com/products/104-53-0.html.

One-pot synthesis of 1,3,4-oxadiazole derivatives was achieved by treatment of 2-((4-(phenoxathiin-2-yl) phthalazin-1-yl)oxy) acetohydrazide with aromatic aldehydes in the presence of cerium(IV) ammonium nitrate in dichloromethane. This facile method was confirmed by the cyclization-oxidation reaction of the corresponding hydrazone by cerium(IV) ammonium nitrate to afford the same 1,3,4-oxadiazoles. Also, the reaction of 2-((4-(phenoxathiin-2-yl)phthalazin-1-yl) oxy) acetohydrazide with aromatic carboxylic acids in the presence of cerium(IV) ammonium nitrate in polyethylene glycol afforded 1,3,4-oxadiazole derivatives. The structural formulae of all products were confirmed and characterized by elemental analyses and spectral data. Most of the synthesized products were evaluated for their antibacterial and antifungal activities and showed potent to weak activity.

Interested yet? Keep reading other articles of 104-53-0, you can contact me at any time and look forward to more communication. COA of Formula: https://www.ambeed.com/products/104-53-0.html.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 696-63-9, Name is 4-Methoxythiophenol, SMILES is SC1=CC=C(OC)C=C1, in an article , author is Reddy, Mudumala Veeranarayana, once mentioned of 696-63-9, Name: 4-Methoxythiophenol.

A simple, efficient, and green practical approach to 1H-pyrazolo[1,2-b]phthalazine-5,10-diones from phthalhydrazide, aldehydes, and malononitrile/ethyl cyanoacetate has been developed that uses inexpensive and readily available InCl3 as a catalyst in solvent-free one-pot three-component cyclo condensation reaction. This method should provide high yields, shorter reaction time, easy work-up, purification of products by nonchromatographic method, and cleaner reaction. It is a new strategy for N-fused heterocycles synthesis, which haswider application in organic and medicinal chemistry. (c) 2013 Elsevier Ltd. All rights reserved.

Interested yet? Read on for other articles about 696-63-9, you can contact me at any time and look forward to more communication. Name: 4-Methoxythiophenol.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 103-36-6, Name is Ethyl cinnamate, formurla is C11H12O2. In a document, author is Kerru, Nagaraju, introducing its new discovery. Name: Ethyl cinnamate.

An eco-friendly and efficient green protocol is developed for the synthesis of sixteen pyrazolo-phthalazine derivatives (5a-p) by using inexpensive biodegradable eggshell powder (ESP) as a heterogeneous catalyst. The four-component one-pot condensation reaction proceeded through Knoevenagel-Michael reaction of different chosen active methylene compounds, phthalic anhydride, and hydrazine hydride with various substituted aromatic aldehydes in the water at 60 degrees C, and furnished the high yields of products (93-98%) in rapid reaction time of 28 to 45 min. The material was characterized by different analytical techniques (SEM, TEM, XRD, BET, and FT-IR), and was composed of the high percentage of calcium oxides and carbonates, and less percentage of Na and Mg elements (based on EDX analysis). The ESP material displayed recyclability (4 times) without any notable loss of catalytic efficacy. Besides, this procedure offers 98% of the atom economy and 100% of carbon efficiency together with significant fiscal and enviro-friendly benefits.

If you are hungry for even more, make sure to check my other article about 103-36-6, Name: Ethyl cinnamate.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

In an article, author is Rastogi, Shiva K., once mentioned the application of 5509-65-9, HPLC of Formula: https://www.ambeed.com/products/5509-65-9.html, Name is 2,6-Difluoroaniline, molecular formula is C6H5F2N, molecular weight is 129.11, MDL number is MFCD00007655, category is phthalazine. Now introduce a scientific discovery about this category.

Two protocols for oxygenation of aromatic C-H bonds ortho-positioned to the phthalazine ring were developed. The transannulation of the phthalazine ring to a naphthalene moiety by an Inverse Electron Demand Diels-Alder (IEDDA) reaction led to the synthesis of naphtho[2,1-c]chromenes, 1-(ortho-hydroxyaryl)naphthalenes and 6,7-dihydrobenzo[b]naphtho[1,2-d]oxepine. This new strategy based on the utilization of transformable nitrogen heterocycles in C-H functionalization chemistry can be potentially applicable to the synthesis of a broad range of biaryl compounds.

If you are interested in 5509-65-9, you can contact me at any time and look forward to more communication. HPLC of Formula: https://www.ambeed.com/products/5509-65-9.html.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry is an experimental science, Recommanded Product: 140-75-0, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 140-75-0, Name is (4-Fluorophenyl)methanamine, molecular formula is C7H8FN, belongs to phthalazine compound. In a document, author is Bakherad, Mohammad.

The reaction of 1-chloro-4-propargylaminophthalazine with various aryl halides catalyzed by Pd-Cu in the presence of potassium carbonate, as the base, in water leads to the one-pot formation of new derivatives of 3-aryl-substituted-6-chloroimidazo-[2,1-a]phthalazines in moderate-to-good yields. Their structures are confirmed by IR and NMR spectra as well as elemental analyses. All the compounds prepared are screened invitro for their anti-bacterial activities. The preliminary results indicate that some target compounds exhibit promising anti-bacterial potency.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 140-75-0. Recommanded Product: 140-75-0.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 611-73-4, Name is 2-Oxo-2-phenylacetic acid, molecular formula is C8H6O3. In an article, author is Jahanshahi, Parivash,once mentioned of 611-73-4, Recommanded Product: 611-73-4.

A novel one-pot four-component, highly efficient and environmentally benign approach for the synthesis of a wide range of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives in the presence of acetic acid functionalized imidazolium salt (1-carboxymethyl-2,3-dimethylimidazolium iodide {[cmdmim]I}) as a newly synthesized BrOnsted acid catalyst is described. The reaction occurs via tandem Knoevenagel-cyclocondensation of phthalic anhydride, hydrazine hydrate, aromatic aldehydes and 3-(1-methyl-1H-pyrrol-2-yl)-3-oxopropanenitrile (or 3-(1H-indol-3-yl)-3-oxopropanenitrile) in the presence of acetic acid functionalized imidazolium salt {[cmdmim]I} in ethanol under reflux conditions. This adequate procedure possesses some advantages like atom economy, cost-effectiveness, operational simplicity, short reaction times, straightforward work-up procedure, high yields, and reusability of the catalyst in 5 consecutive runs without any appreciable decrease in activity.

Interested yet? Keep reading other articles of 611-73-4, you can contact me at any time and look forward to more communication. Recommanded Product: 611-73-4.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem