Tag: M.W=150-200

Formula: C7H5NO4. Kumar, M; Verma, S; Verma, AK in [Kumar, Manoj; Verma, Shalini; Verma, Akhilesh K.] Univ Delhi, Dept Chem, Delhi 110007, India published Ru(II)-Catalyzed Oxidative Olefination of Benzamides: Switchable Aza-Michael and Aza-Wacker Reaction for Synthesis of Isoindolinones in 2020.0, Cited 65.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7.

Selective tandem oxidative C-H olefination-azaMichael/aza-Wacker reaction of N-arylbenzamides is achieved by fine-tuning between base and additive to access valuable 3-oxoisoindolinyls and 3-oxoisoindolinylidenes, respectively. Careful optimization and control experiments provides a guiding principle in the design of a proposed catalytic cycle. The copper-iminium complex acting as a precursor for the binding of Ru catalyst was isolated and confirmed by X-ray diffraction. The versatility of this catalytic system has been demonstrated by the synthesis of biologically relevant molecules.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Kumar, M; Verma, S; Verma, AK or concate me.. Formula: C7H5NO4

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

An article Synthetic aluminosilicate based geopolymers – Second generation geopolymer HPLC stationary phases WOS:000482179800023 published article about INTERACTION LIQUID-CHROMATOGRAPHY; POROUS GRAPHITIC CARBON; RETENTION BEHAVIOR; PERFORMANCE; METAKAOLIN; COLUMNS; SELECTIVITY; SUSPENSION; PACKING; MODE in [Thakur, Nimisha; Wahab, M. Farooq; Khanal, Durga D.; Armstrong, Daniel W.] Univ Arlington, Dept Chem & Biochem, Arlington, TX 76019 USA in 2019.0, Cited 46.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. Computed Properties of C7H5NO4

A survey of existing stationary phases classified by the United States Pharmacopeia reveals that 120 groups of chromatographic supports mostly utilize silica-silane chemistry, polymeric materials along with some niche metal oxides. In this work, the synthesis and characterization of transition-metal free geopolymers as a new class of stationary phases for hydrophilic interaction liquid chromatography and normal phase separations is reported. The geopolymers were synthesized by reaction of synthetic aluminosilicate with potassium silicate (fumed silica dissolved in KOH) in a water-in-oil emulsion. For comparative purposes of peak shapes, a geopolymer from natural metakaolin was also synthesized. The geopolymers were examined by X-ray diffraction, energy dispersive spectroscopy, laser diffraction, and N-2-adsorption isotherms. This two-step approach gives spherical microparticles with surface area and pore size comparable to silica phases (150 m(2)/g and 120 angstrom respectively). Both synthetic aluminosilicates based and natural metakaolin based geopolymers occupy a unique spot in the HILIC selectivity chart when compared to 35 HILIC phases. An additional promising feature of geopolymers is high pH and temperature stability which are used to tune selectivity for small polar analytes. High pH separations are shown with carboxylic acids. Geopolymers also show mixed mode behavior in retention with ion-exchange properties in purely aqueous mobile phases. The separation of derivatized sugars is demonstrated and compared with porous graphitic carbon (Hypercarb (TM)) as another pH-stable stationary phase. (C) 2019 Elsevier B.V. All rights reserved.

Computed Properties of C7H5NO4. About 4-Nitrobenzoic acid, If you have any questions, you can contact Thakur, N; Wahab, MF; Khanal, DD; Armstrong, DW or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

An article Asymmetric Michael Addition of Unactivated Ketones with beta-Nitrostyrenes Mediated by Bifunctional L-Prolinamide Organocatalysts WOS:000516865300011 published article about ENANTIOSELECTIVE CONJUGATE ADDITION; CARBONYL-COMPOUNDS; NITROOLEFINS; CATALYSIS; CYCLOHEXANONE; NITROALKANES; CONSTRUCTION; DERIVATIVES; ACID; 3-HYDROXY-2-OXINDOLES in [Rani, Dixita; Bhargava, Meha; Agarwal, Jyoti] Panjab Univ, Dept Chem, Chandigarh 160014, India; [Rani, Dixita; Bhargava, Meha; Agarwal, Jyoti] Panjab Univ, Ctr Adv Studies, Chandigarh 160014, India in 2020.0, Cited 102.0. SDS of cas: 62-23-7. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7

The catalytic activity of two types of L-prolinamide organocatalysts was investigated for asymmetric Michael addition reaction of cyclic/acyclic ketones with beta-nitrostyrens. L-Prolinamides bearing amino groups on phenyl ring worked well, though their catalytic efficiency as well as selectivity was found to be dependent upon the position of amine group to the amide bond. Organocatalyst having -NH2 group ortho to amide bond provided the best results. Substrate scope was also studied by performing the reaction of various beta-nitrostyrenes with ketones to afford the corresponding Michael adducts in excellent yields with very high diastereoselectivities and enantioselectivities in almost all cases.

SDS of cas: 62-23-7. About 4-Nitrobenzoic acid, If you have any questions, you can contact Rani, D; Bhargava, M; Agarwal, J or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

In 2019.0 CHEM-EUR J published article about CARBON-DIOXIDE; IONIC LIQUIDS; REDUCTIVE FUNCTIONALIZATION; FLUORIDE; KETONES; HYDROSILANES; HYDROSILYLATION; METHYLATION; FORMAMIDES; ACTIVATION in [Hulla, Martin; Ortiz, Daniel; Vasilyev, Dmitry; Dyson, Paul J.] Ecole Polytech Fed Lausanne, Inst Chem & Chem Engn, CH-1015 Lausanne, Switzerland; [Katsyuba, Sergey] RAS, FRC, Kazan Sci Ctr, Arbuzov Inst Organ & Phys Chem, Arbuzov St 8, Kazan 420088, Russia in 2019.0, Cited 57.0. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7. HPLC of Formula: C7H5NO4

N-formylation of amines with CO2 is base-catalyzed and studies of salt catalysts reveal that the reaction is efficiently catalyzed by free floating anions of high basicity, as represented in the cover image. More information can be found in the Full Paper by P. J. Dyson et al. (DOI: 10.1002/chem.201901686).

About 4-Nitrobenzoic acid, If you have any questions, you can contact Hulla, M; Ortiz, D; Katsyuba, S; Vasilyev, D; Dyson, PJ or concate me.. HPLC of Formula: C7H5NO4

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Authors Nejad, MJ; Salamatmanesh, A; Heydari, A in ELSEVIER SCIENCE SA published article about EFFICIENT HETEROGENEOUS CATALYST; SCHIFF-BASE COMPLEX; SELECTIVE OXIDATION; AEROBIC OXIDATION; CARBOXYLIC-ACID; PYRIDINIUM CHLOROCHROMATE; RECYCLABLE CATALYST; SECONDARY ALCOHOLS; DIMETHYL-SULFOXIDE; MANGANESE-DIOXIDE in [Nejad, Masoumeh Jadidi; Salamatmanesh, Arefe; Heydari, Akbar] Tarbiat Modares Univ, Chem Dept, POB 14155-4838, Tehran, Iran in 2020, Cited 61. Safety of 4-Nitrobenzoic acid. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7

Copper (II) immobilized on L-arginine-beta-cyclodextrin-functionalized magnetite nanoparticles (nano-Fe3O4@L-arginine-CD-Cu(II)) were successfully synthesized and fully characterized using FT-IR, XRD, SEM, EDX, ICP, TGA and VSM techniques. The catalytic activity of these magnetically retrievable nanoparticles was evaluated in the direct oxidation of primary alcohols and benzyl halides to acids in neat conditions that was observed to proceed well and products were obtained in good yields. In addition to showing good catalytic activity, the magnetic catalyst is easy to synthesize and can be recycled at least five times with little loss in activity. (C) 2020 Elsevier B.V. All rights reserved.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Nejad, MJ; Salamatmanesh, A; Heydari, A or concate me.. Safety of 4-Nitrobenzoic acid

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Authors Kurnar, A; Kumar, N; Sharma, R; Bhargava, G; Mahajan, D in AMER CHEMICAL SOC published article about AMIDE BOND FORMATION; DIPHENYLPHOSPHORYL AZIDE; CONVENIENT REAGENT; SUBSTITUTED UREAS; AMIDATION in [Kurnar, Arun; Kumar, Naveen; Mahajan, Dinesh] Translat Hlth Sci & Technol Inst, Drug Discovery Res Ctr, Faridabad 121001, Haryana, India; [Sharma, Ritika; Bhargava, Gaurav] IK Gujral Punjab Tech Univ, Dept Chem Sci, Kapurthala 144603, Punjab, India in 2019, Cited 50. Recommanded Product: 4-Nitrobenzoic acid. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7

Herein we report, a single-pot multistep conversion of inactivated carboxylic acids to various N-containing compounds using a common synthetic methodology. The developed methodology rendered the use of carboxylic acids as a direct surrogate of primary amines, for the synthesis of primary ureas, secondary/tertiary ureas, O/S-carbamates, benzoyl ureas, amides, and N-formyls, exploiting the Curtius reaction. This approach has a potential to provide a diversified library of N-containing compounds, starting from a single carboxylic acid, based on the selection of the nucleophile.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Kurnar, A; Kumar, N; Sharma, R; Bhargava, G; Mahajan, D or concate me.. Recommanded Product: 4-Nitrobenzoic acid

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Recommanded Product: 62-23-7. Recently I am researching about BIOLOGICAL EVALUATION; CATALYTIC INHIBITORS; N-PHENYLPYRROLAMIDES; GYRASE; OPTIMIZATION; DESIGN; POTENT; N-PHENYL-4,5-DIBROMOPYRROLAMIDES; KIBDELOMYCIN; DERIVATIVES, Saw an article supported by the Slovenian Research AgencySlovenian Research Agency – Slovenia [P1-0208]. Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Skok, Z; Durcik, M; Skledar, DG; Barancokova, M; Masic, LP; Tomasic, T; Zega, A; Kikelj, D; Zidar, N; Ilas, J. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid

Human DNA topoisomerase II is one of the major targets in anticancer therapy, however ATP-competitive inhibitors of this target have not yet reached their full potential. ATPase domain of human DNA topoisomerase II belongs to the GHKL ATPase superfamily and shares a very high 3D structural similarity with other superfamily members, including bacterial topoisomerases. In this work we report the discovery of a new chemotype of ATP-competitive inhibitors of human DNA topoisomerase II alpha that were discovered through screening of in-house library of ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV. Systematic screening of this library provided us with 20 hit compounds. 1,2,4-Substituted N-phenylpyrrolamides were selected for a further exploration which resulted in 13 new analogues, including 52 with potent activity in relaxation assay (IC50 = 3.2 mu M) and ATPase assay (IC50 = 0.43 mu M). Cytotoxic activity of all hits was determined in MCF-7 cancer cell line and the most potent compounds, 16 and 20, showed an IC50 value of 8.7 and 8.2 mu M, respectively.

About 4-Nitrobenzoic acid, If you have any questions, you can contact Skok, Z; Durcik, M; Skledar, DG; Barancokova, M; Masic, LP; Tomasic, T; Zega, A; Kikelj, D; Zidar, N; Ilas, J or concate me.. Recommanded Product: 62-23-7

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Recently I am researching about CARBONYL-COMPOUNDS; AEROBIC OXIDATION; ALCOHOLS; COMPLEXES; SEPARATION; CHEMISTRY; DESIGN; LIGAND; O-2, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21671104]; Jiangsu Key Technology RD Program [BE2016010, BE2016010-1]; Natural Science Foundation ofJiangsu Higher Education Institutions of China [1 7KJA430010, 15KJA350002]; Priority Academic Program Development ofJiangsu Higher Educational Institutions; Jiangsu Collaborative Innovation Center of Biomedical Functional Materials; State Key Laboratory of Coordination Chemistry in Nanjing UniversityNanjing University. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Zhou, J; Xu, HF; Huang, YY; Cao, CN; Han, J; Zhao, XL; Chen, XD. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid. COA of Formula: C7H5NO4

Visible-light driven photoreactions using metal-organic frameworks (MOFs) as catalysts are promising with regard to their environmental friendly features such as the use of renewable and sustainable energy of visible light and potential catalyst recyclability. To develop potential heterogeneous photocatalysts, a family of three copper(II) coordination polymers bearing different Cu-O assemblies have been synthesized with the ligand 4,4′-disulfo-[1,1′-biphenyl]-2,2′-dicarboxylate acid (H4DSDC), namely, {[Cu-7(DSDC)(2)(OH)(6)(H2O)(10)]center dot xH(2)O}(n) (1), {[Cu-4(DSDC)(4,4′-bpy)(2)(OH)(4)]center dot 2H(2)O}(n) (2), and (Cu-2(DSDC)(phen)(2)(H2O)(2)}(n) (3) (4,4′-bpy = 4,4′-bipyridine and phen = 1,10-phenanthroline). Complex 1 represents a metal-organic framework featuring a NbO type topology constructed from the infinite linkage of heptanuclear [Cu-7(mu(3)-OH)(6)(H2O)(10)](8+) clusters by deprotonated DSDC4- ligands, comprising one-dimensional hexagonal channels of a diameter around 11 angstrom that are filled with water molecules. The infinite waving {[Cu-2(OH)(2)](2+)}(n) ladderlike chains in complex 2 are bridged by DSDC4- and 4,4′-bpy ligands into a three-dimensional framework. A two-dimensional layered structure is formed in complex 3 due to the existence of terminal phenanthroline ligands. All of the coordination polymers 1-3 are able to catalyze the visible-light driven oxidation of alcohols at mild conditions using hydrogen peroxide as an oxidant, in which complex 1 demonstrates satisfactory efficiency. Significantly for this photoreaction catalyzed by 1, the extent of oxidation over aryl primary alcohols is fully controllable with time-resolved product selectivity, giving either corresponding aldehydes or carboxylate acids in good yields. It is also remarkable that the photocatalyst could be recovered almost quantitatively on completion of the catalytic cycle without any structure change, and could be recycled for catalytic use for at least five cycles with constant efficiency. This photocatalyst with time-resolved selectivity for different products may provide new insight into the design and development of novel catalytic systems.

COA of Formula: C7H5NO4. About 4-Nitrobenzoic acid, If you have any questions, you can contact Zhou, J; Xu, HF; Huang, YY; Cao, CN; Han, J; Zhao, XL; Chen, XD or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Jiang, RR; Lu, GH; Yan, ZH; Wu, DH; Zhou, RR; Bao, XH in [Jiang, Runren; Lu, Guanghua; Yan, Zhenhua; Wu, Donghai; Zhou, Ranran; Bao, Xuhui] Hohai Univ, Coll Environm, Minist Educ, Key Lab Integrated Regulat & Resources Dev Shallo, Nanjing 210098, Jiangsu, Peoples R China; [Lu, Guanghua] Tibet Agr & Anim Husb Univ, Water Conservancy Project, Linzhi 860000, Peoples R China; [Lu, Guanghua] Tibet Agr & Anim Husb Univ, Civil Engn Coll, Linzhi 860000, Peoples R China published Insights into a CQD-SnNb2O6/BiOCl Z-scheme system for the degradation of benzocaine: Influence factors, intermediate toxicity and photocatalytic mechanism in 2019.0, Cited 50.0. SDS of cas: 62-23-7. The Name is 4-Nitrobenzoic acid. Through research, I have a further understanding and discovery of 62-23-7.

The development of a novel Z-scheme system with a high separation efficiency of the charge carriers for remarkably enhanced photocatalytic activity is highly desirable. Herein, a carbon quantum dot-modified SnNb2O6/BiOCl (CQD-SNO/BOC) Z-scheme system, in which the CQDs acted as a bridge for the charge carriers, was successfully synthesized. As expected, the CQDs acted as a bridge for the charge carriers that could separate and accumulate electrons from SnNb2O6 and holes from BiOCl by promoting the transfer of the photoinduced charge carriers, which enabled the BiOCl holes to maintain their high oxidation capability. Additionally, the CQDs not only endowed the SNO/BOC Z-scheme system with a large specific surface area that provided a greater number of active sites but also noticeably improved its visible light absorption capacity. Therefore, the CQDSNO/BOC Z-scheme system showed an improved photocatalytic performance for the degradation of benzocaine (BC), which was over 20 times, 10 times and 2 times greater than those of BiOCl, SnNb2O6 and SNO/BOC Z-scheme systems, respectively. In addition, the effects of catalyst concentration, pH value, different anions, and humic acid (HA) concentration on the photodegradation of BC were investigated in depth. Simultaneously, a four-stage pathway for the degradation of BC was proposed based on the degradation products that were identified, and the accuracy of this pathway was further verified based on biotoxicity assessments and toxicity predictions of the products. According to the ESR spectra and active species trapping experiments, a mechanism for the CQD-SNO/BOC Z-scheme system was proposed, in which the CQD bridge accelerated charge transfer. Based on these results, the CQD-modified Z-scheme system could be an efficient and promising photocatalyst for the degradation of PPCPs in water.

SDS of cas: 62-23-7. About 4-Nitrobenzoic acid, If you have any questions, you can contact Jiang, RR; Lu, GH; Yan, ZH; Wu, DH; Zhou, RR; Bao, XH or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Recently I am researching about 3CL PROTEASE INHIBITORS; BIOLOGICAL EVALUATION; TANDEM REACTION; SELECTIVE INHIBITORS; DESIGN; DERIVATIVES; POTENT; ARYL; OXAZOLES; KETONES, Saw an article supported by the Natural Science Foundation of Jiangsu ProvinceNatural Science Foundation of Jiangsu Province [BK20171184]; Jiangsu Planned Projects for Postdoctoral Research Funds [1701132C]; Technology Plan Projects of Xuzhou [KC17091]; Postgraduate Research & Practice Innovation Program of Jiangsu Province [KYCX18-2203]. Category: phthalazines. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Huang, TH; Wu, X; Yu, YB; An, L; Yin, XX. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid

A convenient and efficient strategy for the synthesis of 2-acyl benzothiazoles/thiazoles has been developed. The treatment of benzothiazole/thiazole with allylic Grignard reagents readily generates the corresponding 2-Grignard reagents, which is followed by a reaction with N,N’-carbonyldiimidazole activated carboxylic acids to afford various 2-acyl benzothiazoles/thiazoles products. The synthetic method is applicable to a wide array of carboxylic acids and allows easy access to 2-acyl benzothiazoles/thiazoles with considerable yields under mild reaction conditions. (C) 2019 Elsevier Ltd. All rights reserved.

Category: phthalazines. About 4-Nitrobenzoic acid, If you have any questions, you can contact Huang, TH; Wu, X; Yu, YB; An, L; Yin, XX or concate me.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem