Archives for Chemistry Experiments of 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid

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PHTHALAZINONE DERIVATIVES

A compound of the formula (I): wherein: A and B together represent an optionally substituted, fused aromatic ring; X and Y are selected from CH and CH, CF and CH, CH and CF and N and CH respectively; RC is selected from H, C1-4 alkyl; and R1 is selected from C1-7 alkyl, C3-20 heterocyclyl and C5-20 aryl, which groups are optionally substituted; or RC and R1 together with the carbon and oxygen atoms to which they are attached form a spiro-C5-7 oxygen-containing heterocyclic group, which is optionally substituted or fused to a C5-7 aromatic ring.

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N747 – PubChem

Awesome Chemistry Experiments For 4-(4-Chlorobenzyl)phthalazin-1(2H)-one

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2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE HL AND H3 ANTAGONISTS

The present invention relates to compounds of formula (I), and salts thereof, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders, such as allergic rhinitis.

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N715 – PubChem

Extended knowledge of 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid

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763114-26-7, Name is 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid, belongs to phthalazine compound, is a common compound. name: 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acidIn an article, once mentioned the new application about 763114-26-7.

Preparation method of (by machine translation)

The invention relates to a method. 2 – (2 – (4 – Fluoro -3 – carboxyphenyl) acetyl) benzoate and hydrazine reagent undergo a chemical reaction to give 2 – fluorine -5 – ((4 – oxo -3, 4 – dihydrophthalazine -1 – yl) methyl) benzoic acid compound, followed 2 – fluorine -5 – ((4 – oxo -3, 4 – dihydrophthalazine -1 – yl) methyl) benzoic acid and 1 – cyclopropylcarbamoyl piperazine to achieve the preparation. In addition, 2 – (2 – (4 -fluoro -3 – carboxyphenyl) acetyl) benzoate firstly reacts with 1 -cyclopropylformyl piperazine and then undergoes chemical reaction with hydrazine reagent to complete preparation. (by machine translation)

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N770 – PubChem

More research is needed about 763114-26-7

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Different fumarine derivative and its preparation method and application (by machine translation)

The invention discloses a different fumarine the chemical structure of the derivative (the formula ), Through the NICD amino with aryl isocyanate, carboxylic acid, amide carbonyl chloride condensation reaction or NICD with aromatic amino through solid phosgene symmetrical amide prepared by the condensation reaction, the compound has certain in vivo and in vitro anti-cancer activity, can be used as a cancer prevention and treatment of drug application. type Formula In the chemical structure: . (by machine translation)

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N750 – PubChem

Properties and Exciting Facts About 763114-26-7

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 763114-26-7, help many people in the next few years.Formula: C16H11FN2O3

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Formula: C16H11FN2O3, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 763114-26-7, name is 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid. In an article£¬Which mentioned a new discovery about 763114-26-7

PHTHALAZINONE KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL USE THEREOF

A phthalazinone ketone derivative as represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, a use thereof as a poly (ADP-ribose) polymerase (PARP) inhibitor, and a cancer treatment method thereof are described.

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N766 – PubChem

Discovery of 763114-26-7

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Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 763114-26-7

Compound based on ligand-CRBN induced degradation PARP-1 of ligand, as well as preparation method and application thereof (by machine translation)

The compound and the pharmaceutical composition of the CRBN compound disclosed PARP – 1 by the invention can be used for preventing, or treating a human PARP – 1 body, and E3 the compound and the cereblon pharmaceutical composition disclosed by the invention can. be used for preventing or treating a human body and having a great application prospect in, and the field of medicines / PARP – 1, PARP – 1, PARP – 1. (by machine translation)

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N778 – PubChem

More research is needed about 4-(4-Chlorobenzyl)phthalazin-1(2H)-one

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. HPLC of Formula: C15H11ClN2O, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 53242-88-9, in my other articles.

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Microwave-promoted synthesis of some novel 4-(4-methyl-phenyl)-substituted phthalazin-1-one derivatives

In this study, a series of 4-(4-methyl-phenyl)-substituted phthalazin-1-one derivatives have been synthesized with the combination of rapid microwave synthesis and phasetransfer catalyst methodology, which is characterized by very short reaction times and easy workup procedures and which can be exploited to generate some novel phthalazinone heterocycles. Substituted phthalazin-1-one derivatives have been synthesized from phthalyl derivatives as starting material. The structures of these compounds were confirmed by NMR and mass spectral studies.

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N726 – PubChem

Properties and Exciting Facts About 4-(4-Chlorobenzyl)phthalazin-1(2H)-one

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 53242-88-9. In my other articles, you can also check out more blogs about 53242-88-9

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PHTHALAZINONE DERIVATIVES

A method of treatment of a disease of the human or animal body mediated by PARP comprising administering to such a subject a therapeutically effective amount of a compound of formula: 1 or an isomer, salt, solvate, chemically protected form, and prodrug thereof, wherein: A and B together represent an optionally substituted, fused aromaticring; RC is represented by -L-R L, where L is of formula: -(CH2)n1-Q n2-(CH2) n3- wherein n1, n2 and n3 are each selected from 0, 1, 2 and 3, the sum of n1, n2 and n 3 is 1, 2 or 3 and Q is selected from O, S, NH, C(-O) or -CR1R2-, where R1 and R2 are independently selected from hydrogen, halogen or optionally substituted C1-7 alkyl, or may together with the carbon atom to which they are attached form a C3-7 cyclicalkyl group, which may be saturated (a C3-7 cycloalkyl group) or unsaturated (a C3-7 cycloalkenyl group), or one of R1 and R2 may be attached to an atom in RL to form an unsaturated C3-7 cycloalkenyl group which comprises the carbon atoms to which R1 and R2 are attached in Q, -(CH2)n3- (if present) and part of RL ; and RL is optionally substituted C5-20 aryl; and RN is selected from hydrogen, optionally substituted C1-7 alkyl, C3-20 heterocyclyl, and C5-20 aryl, hydroxy, ether, nitro, amino, amido, thiol, thioether, sulfoxide and sulfone

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N718 – PubChem

Archives for Chemistry Experiments of 4-(4-Chlorobenzyl)phthalazin-1(2H)-one

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 53242-88-9, and how the biochemistry of the body works.COA of Formula: C15H11ClN2O

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 53242-88-9, name is 4-(4-Chlorobenzyl)phthalazin-1(2H)-one, introducing its new discovery. COA of Formula: C15H11ClN2O

POTASSIUM CHANNEL MODULATORS

Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein ring Z1, R1, p, R3, and R4 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N714 – PubChem

New explortion of 152265-57-1

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PROTOZOAN PARASITE GROWTH INHIBITORS

Compounds and methods for inhibiting growth of a protozoan parasite. Methods of treating a protozoan parasite infection in a subject by administering a therapeutically effective amount of a compound as disclosed herein. The compounds and methods can be used to inhibit growth of protozoan parasites such as Trypanosoma brucei, Trypanosoma cruzi, Leishmania spp., and Plasmodium spp.

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Reference£º
Phthalazine – Wikipedia,
Phthalazine | C8H6N709 – PubChem