Tag: M.W:200-300

Reference of 58743-75-2, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 58743-75-2, Name is 4′-Ethyl-[1,1′-biphenyl]-4-carbonitrile, SMILES is N#CC1=CC=C(C2=CC=C(CC)C=C2)C=C1, belongs to phthalazines compound. In a article, author is Qaseer, Hanan A., introduce new discover of the category.

Crystallographic Study on the Structure of 5,6,7,8-Tetrahydro-1,4-di (2 ‘-pyridyl) Phthalazine

The solid-state structure of 5,6,7,8-tetrahydro-1,4-di(2’-pyridyl)phthalazine (6-dppn) was characterized by X-ray diffraction and a crystallographic study was then conducted. It was found that 6-dppn exists in the trans/trans conformation. This ligand crystallizes in P2(1)/c(14) space group with unit cell parameters of a = 9.698(2) angstrom, b = 9.999(4) angstrom, c = 10.7268(3) angstrom, beta = 92.890(6)degrees, Z = 8 and V = 2958.2(14) angstrom(3). The non-covalent interactions involved in the structure of 6-dppn were investigated and presented in terms of supramolecular chemistry and crystal engineering.

Reference of 58743-75-2, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 58743-75-2 is helpful to your research.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Synthetic Route of 23981-47-7, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 23981-47-7, Name is 2-(6-Methoxynaphthalen-2-yl)acetic acid, SMILES is O=C(O)CC1=CC=C2C=C(OC)C=CC2=C1, belongs to phthalazines compound. In a article, author is Abd El-Wahab, Ashraf H. F., introduce new discover of the category.

Synthesis and Reactions of Some New Benzylphthalazin-1-ylaminophenols, 2H-Chromene and 5H-Chromeno[2,3-d]pyrimidine Derivatives with Promising Antimicrobial Activities

A series of (4-benzylphthalazin-1-ylamino) phenols 4-6 were prepared. Bromination of (4-benzylphthalazin-1-ylamino) phenol (1) with bromine afforded the bromophenol derivative 7, while condensation of the isomeric (4-benzylphthalazin-1-ylamino) phenol (2) or 7-(4-benzylphthalazin-1-ylamino)naphthalene-2-ol (3) with arylidenemalononitriles 8a-c in ethanol/piperidine solution afforded chromene derivatives 9a-c and 10a,b. Treatment of 7-(4-benzylphthalazin- 1-ylamino)-4-(p-methoxyphenyl)-4H-chromene-3-carbonitrile (9a) with triethyl orthoformate/Ac2O afforded ethoxymethyleneamino derivative 11. Condensation of 9a with DMFDMA/xylene gave chromenopyrimidine derivative 13, while treatment of 9a with Ac2O afforded the N-acetylimino derivative 14. The structures of the newly synthesized derivatives were confirmed by their elemental analysis and spectral data. The antimicrobial activities of some selected compounds were also studied and some of them were found to exhibit promising effects against Gram-positive and Gram-negative bacteria and fungi.

Synthetic Route of 23981-47-7, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 23981-47-7.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 24650-42-8, Name is 2,2-Dimethoxy-2-phenylacetophenone, SMILES is COC(OC)(C(=O)C1=CC=CC=C1)C1=CC=CC=C1, in an article , author is Gan, Min, once mentioned of 24650-42-8, Computed Properties of C16H16O3.

Enantioselective Halolactonizations Using Amino-Acid-Derived Phthalazine Catalysts

Amino-acid-derived phthalazine catalysts have been designed and synthesized for enantioselective halolactonization of prochiral dienoic acids. The scope of the reaction is evidenced by 17 examples of Spiro a-exo-methylene-halolactones with up to 99.8% enantiomeric excess. The resulting enantio-enriched Spiro halolactone products are found to exhibit potent antitumor effects. In addition, both antipodes of products with equally excellent enantioselevity could be obtained since a pair of enantiomeric catalysts is guaranteed.

Interested yet? Read on for other articles about 24650-42-8, you can contact me at any time and look forward to more communication. Computed Properties of C16H16O3.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.1878-68-8, Name is 4-Bromophenylacetic acid, SMILES is OC(=O)CC1=CC=C(Br)C=C1, belongs to phthalazines compound. In a document, author is Savjani, Nicky, introduce the new discover, SDS of cas: 1878-68-8.

Bis(iminopyridyl)phthalazine as a sterically hindered compartmental ligand for an M-2 (M = Co, Ni, Fe, Zn) centre; Applications in ethylene oligomerisation

The new bis(iminopyridyl)phthalazine ligand, 1,4-{(2,6-i-Pr2C6H3)N=CMe)C5H3N}(2)C8H4N2 (L), has been prepared in good yield using a combination of palladium-mediated cross coupling and condensation strategies. Reaction of L with three equivalents of CoX2 (X = Cl, Br) in n-BuOH at elevated temperature generates, on crystallisation from bench acetonitrile, the paramagnetic tetrahalocobaltate salts [(L) Co2X(mu-X)(NCMe)(m)(OH2)(n)](CoX4) (X = Cl, m = 2, n = 1 1a; X = Br, m = 2, n = 0 1b) as acetonitrile or mixed acetonitrile/aqua adducts; a similar product is obtained from the reaction of FeCl2 with L and has been tentatively assigned as [(L)Fe2Cl(mu-Cl)(OH2)(3)](FeCl4) (2). By contrast, reaction of L with NiX2(DME) (X = Cl, Br; DME = 1,2-dimethoxyethane), under similar reaction conditions, affords the halide salts [(L) Ni2X2(mu-X)(OH2)(2)](X) (X = Cl 3a, X = Br 3b) as aqua adducts. Structural determinations on 1 and 3 reveal L to adopt a bis(tridentate) bonding mode allowing the halide-bridged metal centres to assemble in close proximity (M center dot center dot center dot M range: 3.437-3.596 angstrom). Unexpectedly, on reaction of L with ZnCl2, the neutral bimetallic [(L) Zn2Cl4] (4b) complex is formed in which the ZnCl2 units fill inequivalent binding sites within L (viz. the N-phth,N-py,N-im and N-py,N-im pockets). Complex 4b could also be obtained by the sequential addition of ZnCl2 to L to form firstly monometallic [(L) ZnCl2] (4a) and then on further ZnCl2 addition 4b; the fluxional behaviour of diamagnetic 4a and 4b is also reported. On activation with excess methylaluminoxane (MAO), 1-3 display modest activities for ethylene oligomerisation forming low molecular weight waxes with methyl-branched products predominating for the nickel systems (3). On the other hand, the iron catalyst (2) gives exclusively alpha-olefins while the cobalt systems (1) are much less selective affording equal mixtures of alpha-olefins and internal olefins along with lower levels of vinylidenes and tri-substituted alkenes. Single crystal X-ray structures are reported for L, 1a, 1b, 3a, 3b and 4. (C) 2015 Elsevier B.V. All rights reserved.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1878-68-8 is helpful to your research. SDS of cas: 1878-68-8.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 201611-92-9, Name is 4-Cyano-4-((phenylcarbonothioyl)thio)pentanoic acid, molecular formula is C13H13NO2S2. In an article, author is Han, Yi,once mentioned of 201611-92-9, Computed Properties of C13H13NO2S2.

Ag NPs on chitosan-alginate coated magnetite for synthesis of indazolo [2,1-b]phthalazines and human lung protective effects

Biocomposite nanomaterials have been evolved as the new generation catalysts and therapeutic supplement in these days. Magnetically isolation has added new features to this category. This has encouraged us to synthesize a novel Ag NP adorned chitosan-alginate dual bio-polysaccharide (two of the more versatile polysaccharides) modified core-shell magnetic nanocomposite (Fe3O4/CS-Alg/Ag NPs). The material was meticulously characterized following different physicochemical techniques, such as, FT-IR, ICP-OES, FESEM, EDX, atomic mapping, TEM, VSM, XRD and XPS studies. The as synthesized material was catalytically explored in the one-pot multicomponent synthesis of biologically potent 2H-indazolo[2,1-b]phthalazine-trione derivatives involving a wide range of substrates. The reactions were ended up with excellent yields under solvent-free heating conditions. The catalyst recyclability, heterogeneity and leaching tests were performed to ensure its high stability and robustness. It could be reused as much as 10 times in succession with almost unchanged catalytic performances. In the lung protective part of the present research, the human lung toxicity was induced by alpha-Guttiferin. The cell viability of lung MRC-5, CCD-19Lu, WI-38, and BEAS-2B cell lines was measured by trypan blue assay. Caspase-3 activity was assessed by the caspase activity colorimetric assay kit and mitochondrial membrane potential of lung cells was studied by Rhodamine123 fluorescence dye. Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) test was used to show DNA fragmentation and apoptosis of lung cells. Also, the Rat inflammatory cytokine assay kit was used to measure the concentrations of inflammatory cytokines. The catalyst-treated cell cutlers significantly (p <= 0.01) reduced the DNA fragmentation, caspase-3 activity, and inflammatory cytokines concentrations, and raised the mitochondrial membrane potential and cell viability in the high concentration of alpha-Guttiferin-treated lung MRC-5, CCD-19Lu, WI-38, and BEAS-2B cells. The best result of lung protective properties of catalyst against alpha-Guttiferin was seen in the high dose of catalyst i.e., 4 mu g. DPPH test revealed similar antioxidant potentials for catalyst and butylated hydroxytoluene. The catalyst inhibited half of the DPPH molecules in the concentration of 171 mu g/mL. According to the above results, catalyst can be administrated as a lung protective drug for the treatment of lung diseases after approving in the clinical trial studies in humans. (C) 2020 Elsevier B.V. All rights reserved. If you¡¯re interested in learning more about 201611-92-9. The above is the message from the blog manager. Computed Properties of C13H13NO2S2.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

In an article, author is Kiasat, Ali Reza, once mentioned the application of 4271-30-1, Application In Synthesis of (S)-2-(4-Aminobenzamido)pentanedioic acid, Name is (S)-2-(4-Aminobenzamido)pentanedioic acid, molecular formula is C12H14N2O5, molecular weight is 266.25, MDL number is MFCD00042821, category is phthalazines. Now introduce a scientific discovery about this category.

Fe3O4@silica sulfuric acid nanoparticles: An efficient reusable nanomagnetic catalyst as potent solid acid for one-pot solvent-free synthesis of indazolo[2,1-b]phthalazine-triones and pyrazolo[1,2-b]phthalazine-diones

Regarding the green chemistry’s goals, silica-coated magnetite nanoparticles (MNPs) open up new avenue to introduce an amazing and efficient system for facilitating catalyst recovery in different organic reactions. Therefore, in this paper the preparation of sulfuric acid functionalized silica-coated magnetite nanoparticles with core-shell structure (Fe3O4@silica sulfuric acid) are presented by using Fe3O4 spheres as the core and silica sulfuric acid nanoparticles as the shell. The catalyst was characterized by infrared spectroscopy (FT-IR), scanning electron microscope (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) spectroscopy, and vibrating sample magnetometer (VSM). Ability of this nano-magnetic solid acid catalyst in the one-pot three-components condensation reaction of phthalhydrazide, aromatic aldehydes and cyclic or acyclic 1,3-diketones are also described. Utilization of easy reaction conditions, catalyst with high catalytic activity and good reusability, and simple magnetically work-up, makes this methodology as an interesting option for the economic synthesis of indazolo[2,1-b]phthalazine-triones and pyrazolo[1,2-b]phthalazine-diones. (C) 2013 Elsevier B.V. All rights reserved.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

In an article, author is Pisal, Parshuram M., once mentioned the application of 117-34-0, Name is 2,2-Diphenylacetic acid, molecular formula is C14H12O2, molecular weight is 212.2439, MDL number is MFCD00004251, category is phthalazines. Now introduce a scientific discovery about this category, Formula: C14H12O2.

Efficient one-pot three-component synthesis of 2H-indazole [2,1-b]phthalazine-1,6,11(13H)-triones at room temperature

Tetrabutylammonium bromide (TBAB) and cesium carbonate (Cs2O3) catalyzed, one-pot three-component synthesis of 2H-indazole[2,1b]phthalazine-1,6,11(13H)-triones was developed at room temperature in ethanol. Both electron donating and withdrawing groups are compatible under the optimized reaction parameters.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 608141-42-0, Name is (S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine, molecular formula is , belongs to phthalazines compound. In a document, author is Dabiri, Minoo, Quality Control of (S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine.

COMBINING A CLICK-MULTICOMPONENT REACTION: ONE-POT SYNTHESIS OF 1,2,3-TRIAZOL-4-YLMETHYL 3-AMINO-5,10-DIHYDRO-5,10-DIOXO-1H-PYRAZOLO[1,2-b]PHTHALAZINE-2-CARBOXYLATE DERIVATIVES

(1,2,3-Triazol-4-yl)methyl-3-amino-5,10-dihydro-5,10-dioxo-1H-pyrazolo[1,2-b]phthalazine-2-carboxylate derivatives were synthesized by a four-component, one-pot condensation reaction of benzaldehyde derivatives, an active methylene compound (prop-2-ynyl-2-cyanoacetate), azides, and phthalhydrazide in the presence of Cu(OAc)(2)/sodium ascorbate as catalysts and 1-methyl-1H-imidazolium trifluoroacetate ([Hmim]TFA) as an ionic liquid medium in good to excellent yields.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 608141-42-0, in my other articles. Quality Control of (S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Ghorbani-Vaghei, Ramin, once mentioned the application of 108-36-1, Name is 1,3-Dibromobenzene, molecular formula is C6H4Br2, molecular weight is 235.904, MDL number is MFCD00000078, category is phthalazines. Now introduce a scientific discovery about this category, Application In Synthesis of 1,3-Dibromobenzene.

Preparation and characterization of nanomagnetic piperidinium benzene-1,3-disulfonate ionic liquid as a novel, green and heterogeneous catalyst and its use in the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones and 1H-pyrazolo[1,2-a]pyridazine-5,8-diones under solvent-free conditions

The one-pot four-component synthesis of 1H-pyrazolo[1,2-b] phthalazine-5,10-diones and 1H-pyrazolo[1,2-a] pyridazine-5,8-diones was carried out from the reaction between various aldehydes, malononitrile, hydrazine hydrate and phthalic anhydride or maleic anhydride at 110 degrees C in solvent-free conditions using piperidinium benzene-1,3-disulfonate nanomagnetic ionic liquid (NMIL) as a novel and reusable catalyst. Some advantages of the presented procedure are a significant reduction in cost, effective catalysis and reusability of the catalyst. NMIL was thoroughly characterized using Fourier transform infrared spectroscopy, X-ray diffraction, scanning and transmission electron microscopies, thermogravimetry, derivative thermogravimetry, Brunauer-Emmett-Teller analysis, vibrating sample magnetometry and energy-dispersive X-ray spectroscopy. The technique is developed as a suitable and safe method for the synthesis of 1H-pyrazolo[1,2-b] phthalazine-5,10-diones and 1H-pyrazolo[1,2-a] pyridazine-5,8-diones making use of an efficient and reusable green catalyst.

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Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem

Chemistry, like all the natural sciences, Recommanded Product: 4′-Ethyl-[1,1′-biphenyl]-4-carbonitrile, begins with the direct observation of nature¡ª in this case, of matter.58743-75-2, Name is 4′-Ethyl-[1,1′-biphenyl]-4-carbonitrile, SMILES is N#CC1=CC=C(C2=CC=C(CC)C=C2)C=C1, belongs to phthalazines compound. In a document, author is Gong, Wenzheng, introduce the new discover.

A high-strength PPESK/PVDF fibrous membrane prepared by coaxial electrospinning for lithium-ion battery separator

Electrospinning fibrous membranes have attracted a great deal of attention because of their advantages, including uniform pore size, large ratio surface area, and high porosity. For extended application in lithium-ion battery, it is essential to further improve their electrochemical, mechanical, and thermal properties. In this work, a new poly (phthalazine ether sulfone ketone) (PPESK)/polyvinyli-denefluoride (PVDF) core/shell fibrous membrane was fabricated via the coaxial electrospinning technique, followed by hot press. The PPESK/PVDF membrane hot pressed at 160 degrees C exhibits excellent comprehensive performance, including large porosity (80%), high electrolyte uptake (805%), and excellent thermal stability (at 200 degrees C). Moreover, due to the improved bonding effect derived from the solidification of the PVDF shell layer after the hot press, the mechanical property of the membrane is effectively enhanced. The electrochemical tests also indicate that the PPESK/PVDF membrane shows larger ionic conductivity and lower interfacial resistance when compared with commercial microporous polypropylene separator. In addition, simulated cells assembled with the PPESK/PVDF membrane present superior discharge capacity, stable cycle performance, and excellent rate capability. Therefore, the hot-pressed coaxial PPESK/PVDF fibrous membrane has the potential to be a promising candidate as the separator for high-performance lithium-ion battery.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 58743-75-2. Recommanded Product: 4′-Ethyl-[1,1′-biphenyl]-4-carbonitrile.

Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem