Application In Synthesis of 4-Nitrobenzoic acid. Recently I am researching about CHOLINESTERASE-INHIBITORS; ALZHEIMERS-DISEASE; ACETYLCHOLINESTERASE INHIBITORS; CARBONIC-ANHYDRASE; DEMENTIA, Saw an article supported by the WissenschaftsCampus Halle WCH [W13004216]. Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Loesche, A; Wiemann, J; Rohmer, M; Brandt, W; Csuk, R. The CAS is 62-23-7. Through research, I have a further understanding and discovery of 4-Nitrobenzoic acid
The skeleton of the diterpene dehydroabietylamine was modified, and a set of 12-hydroxy-dehydroabietylamine derivatives was obtained. The compounds were screened in colorimetric Ellman’s assays to determine their ability to act as inhibitors for the enzymes acetylcholinesterase (AChE, from electric eel) and butyrylcholinesterase (BChE, from equine serum). Additional investigations concerning the enzyme kinetics were performed and showed 12-hydroxy-N-(4-nitro-benzoyl)dehydroabietylamine (13) and 12-hydroxy-N-(isonicotinoyl)dehydroabietylamine (17) as selective BChE inhibitors holding good inhibition constants K-i = 0.72 +/- 0.06 mu M and K-i = 0.86 +/- 0.19 mu M, respectively.
Application In Synthesis of 4-Nitrobenzoic acid. Welcome to talk about 62-23-7, If you have any questions, you can contact Loesche, A; Wiemann, J; Rohmer, M; Brandt, W; Csuk, R or send Email.
Reference:
Phthalazine – Wikipedia,
,Phthalazine | C8H6N2 – PubChem